Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16439 Ruxolitinib GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 73 KLF13; IKZF1; SIX6; RHOA; ELF2; MNDA; ZNF571; ZNF117; RERE; BACH1; TAL1; RING1; DBP; ZNF85; ZNF22; SOX11; ZNF223; TLE4; AR; ATF7IP; ZKSCAN1; ZNF264; PRDM1; HBP1; RXRA; ZNF430; HIC2; TFEB; CALR; ZNF91; ZEB1; HLX; ZNF12; MDM4; ZKSCAN7; BCL6; IRF9; ZNF665; VPS72; KLF4; IRF8; ARID1A; SALL1; NFE2; TFEC; FLI1; NEUROD1; NR5A2; MEOX2; TCF4; PAX6; JUN; MEIS2; HOXB2; PBX1; TRIM22; ZEB2; SMARCA1; SSX1; ZBTB18; BCL11A; KDM5D; PITX1; WT1; GATA6; NKX3-1; MAFB; ID4; SOX9; MEIS1; BASP1; TXNIP; POU2AF1
Down-regulation 36 USP22; TP53; TFDP1; RFX5; CBFB; SMARCC1; WWP1; SFPQ; HNRNPD; MTDH; EDF1; BRCA1; ELF1; HMGA2; ZNF165; DNAJC1; NR4A2; TGIF2; HTATIP2; PIR; CREM; C1QBP; YWHAB; ATF3; KAT6B; SIM2; THAP11; SCAND1; AHR; HMGN3; ZHX2; HOXC6; FOSB; LITAF; ID1; GATA3