Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16438 Ruxolitinib GSE70138 MCF10A Human 24h 0.12uM EID0006
Types Number Response transcription factors
Up-regulation 26 ZNF274; PPARG; TERF2; ZNF117; TBX2; EMX2; HMGA1; KLF5; MEOX2; INSR; SMAD1; RSF1; HOXB6; HOXB7; ZNF423; DLX2; BCL11A; IFI16; BASP1; MYB; PITX2; DLX5; ID3; TRIM29; TOX3; ID1
Down-regulation 23 TSC22D1; NR2F1; FOSL2; IKBKAP; SAFB2; HDAC1; HOXC10; HLF; HTATIP2; SIAH2; AHR; SOX9; LEF1; MAGED1; RUNX3; THAP11; HMGB3; HMGN3; CD3D; HOXC6; PBX3; ZFP36L1; SATB1