Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16436 Ruxolitinib GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 27 IKZF1; RELB; HOXB6; PPP1R13L; CHD7; MNDA; HOXB7; KLF9; TGFB1; CREB3L1; SAP30; FLI1; TAL1; NCOR2; VEZF1; NFE2; TOB1; FOSL2; SMARCD3; ZFHX4; HES1; ID3; ZEB2; BHLHE40; HOXB2; TRIM29; BASP1
Down-regulation 20 CDK2; ARNT2; ZNF83; SERTAD2; CARHSP1; CRYM; MEIS2; SATB2; SOX2; TBL1XR1; ASCL1; MITF; MKL2; ATF3; ZBTB20; INSM1; TOX; FOXG1; TOX3; GATA6