Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16432 Alpelisib GSE70138 MCF10A Human 24h 0.12uM EID0006
Types Number Response transcription factors
Up-regulation 23 NFATC3; KLF13; IKZF1; RFX5; RBL2; NFAT5; CBFB; RCOR3; MAZ; TGFB1; AES; HDAC1; TFCP2L1; SATB1; FLNA; ID2; HMBOX1; IRF6; AFF1; MEOX1; NR2F2; THAP11; HOXC6
Down-regulation 21 ZEB1; ST18; BASP1; SOX11; ZNF22; EMX2; BNC2; MEIS2; PTTG1; EGR3; NRBF2; ZFP36L2; PITX2; TSC22D1; TOX; OSR2; ZIC1; KLF10; WWTR1; TRPS1; PEG3