Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16430 Alpelisib GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 36 MNT; MKL1; ZMYM2; EGR2; RREB1; IRF8; ZMIZ1; TAF1D; FLNA; TFCP2L1; ZNF580; IRF7; ERBB2; TCF12; FOXC1; CHD8; SMARCC2; SERTAD2; ARID1A; KDM5D; HIRA; MED14; NRBF2; SATB1; NCOR2; ZNF589; BHLHE41; HMGN3; ZFP36L2; ETV5; CREB3L2; HES1; TCF7; TRIM22; NKX3-1; BASP1
Down-regulation 35 KLF1; ZNF576; CCNH; MED6; TDP2; EMX2; SUB1; DLX5; ZNF140; CCNE1; KLF9; NR1D2; ARID4B; ST18; NR4A1; DLX2; ESR1; SMAD1; ZBTB38; ZSCAN31; MEOX2; CREM; ATF3; SHOX2; MSX1; ZSCAN18; TRPS1; HOXC10; TOB1; ID4; TBX3; ZFP36L1; OSR2; HOXB2; ZIC1