Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16429 Alpelisib GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 14 FOXN3; TSC22D3; ZNF623; EGR2; IRF9; NRBF2; BACH2; SOX11; TOX; SATB2; MYBL1; VPS72; DACH1; ZEB2
Down-regulation 21 CITED1; SREBF1; TRIM28; NR1D2; NPM1; RBBP7; HIRA; BHLHE41; ZMYND8; SLC2A4RG; HEY1; HEY2; DLX5; HOXC10; LEF1; PIR; ESR1; MSX1; TRPS1; PEG3; SUV39H1