Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16428 Alpelisib GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 149 CALCOCO1; PAWR; PBXIP1; ZNF217; CSDC2; CITED2; IRF9; TFAP2C; CBX7; CRYM; MYB; FOXN3; CTBP2; PRDM2; TLE4; ZNF117; ZBTB20; IRF6; TGIF1; TCF7L2; TSC22D3; ZSCAN18; AR; ZNF500; PBX1; HBP1; BCL11A; SALL2; SPI1; INSR; HINFP; KLF11; NCOA3; NANOG; ZMIZ1; E2F8; POU5F1B; ZFPM2; ZHX2; ZNF75D; JUP; PBX3; ZNF665; NR4A1; THRA; ZNF124; ZNF611; ZSCAN31; NFE2L3; ZNF85; BNC2; ELF4; TFEC; ZNF135; HIPK1; ZNF239; KAT2B; SOX13; MYRF; ZNF257; MNDA; NFATC4; ZNF329; HMGXB4; HMGB3; ZNF544; PNRC1; LIN28A; GLI2; ARID1A; HNF4G; ARNT2; GATA6; ZNF345; SOX3; ZNF331; CHD8; ELF3; BARX1; ZNF165; REL; MYCL; TBX3; PHIP; NR5A2; SMAD3; HDAC9; ZNF160; ZNF91; EHF; ZBTB18; BTG1; TOB1; ZKSCAN1; ARID5B; WT1; ZBED1; TCF4; CUX2; WNT4; ERBB2; SOX4; HLX; ARL2BP; NR4A2; LMCD1; MYBL1; WWC1; TRIB3; SIAH2; ID4; EP300; ZNF12; ZBTB16; HHEX; SPDEF; TBL1XR1; ERBB4; ZNF711; HOXB2; SOX2; FOXE1; TCF21; MED13; TSC22D1; ZNF423; TRIM22; ZNF721; CUX1; ZNF131; ZNF512B; FOSB; CHD9; BASP1; POU2AF1; CREB3L2; VPS72; CBFA2T3; HOXD1; ZNF589; TP63; MEIS2; OSR2; LOXL2; ETS2; AEBP1; NKX2-1; FOS; KDM5D
Down-regulation 76 FOSL1; PUF60; RELA; RUVBL2; EGR1; TLE1; DNAJC2; SUB1; EDF1; RBPJ; NFYA; MSX1; NUP62; ASH2L; NACA; PITX1; PTTG1; PA2G4; HLTF; CARM1; FLNA; RNF4; BRPF1; TRIM28; SSRP1; ETS1; NPM1; YBX1; CBFB; HNRNPD; CITED1; LEF1; FOXG1; CTR9; STAT5B; EYA2; SMARCE1; RBM14; MTDH; HEY1; ELK3; TAF10; SFPQ; ELF1; CBX6; MED1; HMGA1; HMGB1; C1QBP; SIX1; CRY1; ENO1; SOX9; PURA; CCDC59; RUNX3; HOXC6; NR1D2; ZFHX4; CENPF; SMAD7; BMI1; PIR; HMGB2; NR2F1; MECOM; SERTAD2; NR2F2; SATB2; HOXC10; THAP11; CD3D; ZIC1; MAFB; EGR2; SUV39H1