Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16427 Nvp-bez235 GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 360 HBP1; CALCOCO1; BRWD1; ZNF117; HDAC5; IRF9; BPTF; PBXIP1; PRDM2; ZNF671; KLF13; TSHZ2; CRX; ZNF345; ZNF362; PNRC1; DYRK1B; ZNF415; GLI2; CDIP1; SPI1; ERBB4; IRF6; ZNF571; ZNF667; ZNF33B; NAB2; HOXB1; NEUROG1; ZNF250; FOXN3; ZNF223; ZNF354A; CBX4; NFATC3; ZNF197; INSR; ZNF573; ZNF500; ING4; CAMTA2; ZNF426; ZNF112; NR5A1; AFF2; ZNF688; HINFP; ZNF358; ZKSCAN4; ZBTB7B; ZNF224; ZNF264; CIR1; RARG; ZNF835; ZNF141; SALL2; ZNF154; MNT; SIX6; ZBTB44; ZNF768; ZNF682; HMGA2; ZNF665; THRB; CEBPE; JUP; FEZF2; MEF2D; CHD2; PRDM12; TBX4; ZFP30; TCEA2; HOXD1; ZNF606; HMBOX1; CBFA2T3; NFATC1; CSDC2; KLF3; ZNF135; ZNF701; TFAP2A; RING1; HEYL; ZBTB3; SOX18; KLF11; MAML3; ZNF235; ZNF304; ZNF623; ZSCAN18; TCF3; SOX4; BNC1; ZNF814; SUPT6H; MEF2C; E2F5; PRDM9; ZNF132; ZNF549; BTF3; MYF5; SCAI; FOXK2; EPAS1; EP300; OVOL1; ZNF91; UBE2B; BARX1; ZNF43; PROP1; ZNF81; CREBL2; ZNF225; EMX1; MED12; SUPT3H; LHX2; ZKSCAN1; ZKSCAN7; CBX7; BACH2; PRDM14; ZNF140; OVOL2; ZNF506; SUPT7L; ZNF440; TRPS1; ZNF711; SP100; ZNF529; HOXC13; ZNF550; ZNF239; TGFB1; ZFPM2; CARF; HDAC9; ZNF85; TP73; PAX9; HNF4G; ZNF217; MEOX2; NLK; NEUROD2; TGIF1; L3MBTL1; TAF6L; ZNF214; IRF7; ZNF257; TP63; STAT2; HIC1; LZTR1; SOX9; SRCAP; NFATC4; KLF7; ZSCAN9; GBX2; REL; DCC; ZNF536; TBX5; VHL; TULP1; RFX3; POU6F1; ZNF695; DLX4; SOX12; NR1I3; THRA; YAP1; SETDB1; EGR1; PRRX1; THAP9; ZNF780B; TBX6; PPP1R13L; BCL3; ZNF177; BTG1; EN1; SRY; POU6F2; MLLT10; EZH1; GSC2; ZNF423; MXI1; MYCL; TBX1; GFI1B; ZNF674; PEX14; ELF4; HLX; LHX3; ZNF407; ZNF155; ZNF34; KDM5C; BCL11A; ZNF80; AES; ZBTB16; ZNF302; BAZ2B; MED13; TSC22D3; ZNF75D; ZNF195; SKIL; CERS4; ZNF93; MED17; HIPK2; HESX1; BHLHE41; ZHX2; ERBB2; SOX2; SIRT2; ZNF83; ZNF350; TAL1; ZNF10; BAZ2A; INSM1; TCF7L1; ID1; ZFP69B; SKI; ATOH1; ZBTB43; FOXF1; POU2F2; LDB1; ZNF165; ATN1; TGFB1I1; ZBTB20; TBX2; ID4; SMARCC2; BNC2; TCF4; PAWR; GRHL2; ZNF334; ARNT2; ZNF268; NR1I2; ZNF254; ZMYND8; SOX3; ATF7IP; ARID1A; FOXF2; ZNF430; ZFP36L2; IKZF3; ZNF232; ZEB1; ACTL6B; FOSL2; ZNF512B; FOXA1; JAK2; PKNOX2; ZNF544; NCOA2; ZNF331; PBX1; WNT4; NFE2; NPAS2; NEUROD1; ZNF611; STAT6; SOX11; ST18; CUX2; NFE2L1; RSF1; TGIF2; TRIM29; MYRF; PTRF; ZNF589; MECP2; NKX2-1; NR5A2; HEY2; FLI1; SPIB; MEOX1; SOX17; HOXB2; KLF6; LMCD1; PITX2; SIX3; CREB3L2; SOX13; TCF7L2; PHIP; PDLIM1; BACH1; GATA6; SNAI2; ZBED2; APEX1; NR2F1; BRD4; ZNF160; ASCL1; VPS72; TCF21; TULP3; JUND; KDM5B; ID3; TFEC; ARID5B; HEY1; TRIM22; TXNIP; NR4A2; PAX6; PGR; ARID3A; POU2AF1; THAP11; SMARCA1; TRIB3; FOS; DACH1; MEIS2; ZFP36L1; IFI16; HLF; TWIST1; RELB; SATB1; PBX3; MECOM; CREB1; MEIS1
Down-regulation 86 EZH2; MYCBP; TCERG1; ITGB3BP; TFDP1; GTF2A2; RUVBL2; RUVBL1; CDK2; EED; PUF60; PARP1; CCNA2; MYBL2; NUP62; FOSL1; HSF2; SFPQ; RFX5; CRY1; PTTG1; GABPB1; ZNF672; BMI1; FOXM1; TP53; SSRP1; DNAJC2; HLTF; RBM14; UBP1; CBFB; BRCA1; SUB1; PA2G4; DEK; CENPF; RNF6; GMNN; TBPL1; MLX; NFIL3; NR2F2; TRIM28; SAP30; CCDC59; BCLAF1; RNF138; C1QBP; WHSC1; RAN; CDC5L; RBBP7; PURA; BAZ1B; MED1; TFAM; FUBP1; DNAJC1; BLM; CEBPZ; CCNC; MTDH; PSMC3IP; RBBP4; PMS1; ENO1; DNMT3B; SMARCA2; HOXC6; XBP1; HSBP1; ECD; BBX; HOXB7; HMGB2; CTR9; LEF1; EYA2; TRRAP; ADRB2; ID2; PIR; TSC22D1; MAFB; SUV39H1