Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16426 Nvp-bez235 GSE70138 MCF10A Human 24h 0.12uM EID0006
Types Number Response transcription factors
Up-regulation 161 NR3C1; CALCOCO1; HBP1; PBXIP1; MNT; PRDM2; SOX4; MAFF; ATF4; KLF6; NEUROG1; NAB2; SPI1; HDAC5; ZNF117; MED12; IRF9; EGR1; OVOL2; ZNF536; SMAD3; TSC22D3; HMGA2; FOXN3; TAL1; HOXD1; ZNF74; FOXO3; FLNA; UBE2B; TSG101; FOXD1; SRCAP; RBPJ; IRF7; MAF; NCOA2; ID2; ZNF415; ZNF358; CREBL2; NHLH2; KLF7; ZNF331; AFF2; KLF4; ST18; PNRC1; STAT2; STAT6; ZNF354A; ZNF688; ZNF606; NR4A2; ELF3; ZNF665; ELF4; ZNF91; ZNF141; CBX7; PRRX2; RUNX1; ZNF500; SETDB1; ZMYND8; FOXO4; GFI1B; ING4; SP110; HDAC9; TGFB1; KLF3; SP100; TCF7L2; SUPT6H; KLF11; BTG1; ZNF93; ARID1A; PCGF3; EZH1; MEOX2; DLX4; ERBB2; MXI1; ZNF611; IRF6; ZNF33B; TFCP2L1; NFE2L1; BCL3; TP63; IRF8; ZBED1; TCF7L1; HMBOX1; TCEA2; PDLIM1; ZNF264; EPAS1; FLI1; JUNB; NFATC4; PFDN5; ZBTB43; ZNF423; ZSCAN18; ARID3B; ZNF160; ZFPM2; PPARGC1A; ZBTB16; EP300; CEBPA; PHF20; IFI16; NEUROD1; TERF1; CERS4; FOSL2; REL; JUP; TXNIP; TFEC; TCF4; JAK2; SIX2; EBF2; ARNT2; TBX1; SOX9; NR1H3; NR1H4; KDM5B; TRIM22; FOSB; FOXF2; NR1H2; GATA6; PCGF2; NR4A3; ID3; HTATIP2; TGFB1I1; KLF2; VPS72; OSR2; ZBTB20; HOXB2; NRIP1; ATF3; RBPMS; PITX2; PBX1; NKX2-1; EGR2; FOS; ID1; BASP1; RELB; ZIC1
Down-regulation 77 PUF60; TFDP1; MYCBP; EZH2; MYBL2; HSF2; CDK2; FOSL1; RUVBL1; GTF2A2; PARP1; TCERG1; SUB1; FOXM1; TP53; CCNA2; EED; GMNN; BRCA1; TBP; RFX5; CRY1; BAZ1B; CBFB; RBM14; PA2G4; CHAF1B; TAF5; WDR77; PTTG1; MED6; RUVBL2; ETV1; BCLAF1; PSMC3IP; TFAM; DEK; NUP62; ITGB3BP; DNAJC2; NR2F6; MED21; LEF1; C1QBP; ZNF443; DR1; RAN; HNRNPD; CENPF; E2F6; CCNE1; ZNF410; SFPQ; HLTF; BLM; MTF2; RBBP7; RNF6; ZBTB18; HMGB2; CEBPZ; RBBP8; ENO1; NR2F2; BAZ1A; BMI1; CTR9; TAF9B; STAT1; WT1; ADRB2; IRX5; HOXC6; DNMT3B; TOB1; SUV39H1; SATB1