Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16425 Nvp-bez235 GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 268 CALCOCO1; HBP1; ZNF91; ZNF117; PBXIP1; IRF9; ZNF224; HOXB1; CIR1; FHL2; CRX; CAMTA2; HDAC5; ERBB4; MNT; CSDC2; ZNF362; NFATC3; PRDM2; NAB2; ZNF358; CBX7; DYRK1B; ZNF264; ZKSCAN4; MEF2D; EMX1; ZNF665; NR5A1; ZNF768; NEUROG1; HOXD3; MYBL1; TBX4; ZKSCAN1; HDAC9; BHLHE41; ZNF415; ING4; ALX3; NCOA3; CREBL2; SOX4; HIF3A; IRF6; ZNF667; SPI1; ZNF345; EVX1; KLF7; ZMIZ1; TSHZ2; SIX6; SRCAP; FOXO3; ZNF33B; ZNF354A; HMGA2; PNRC1; ZFHX2; TSG101; ZNF223; TBX21; KLF13; IRF5; CDIP1; ZBTB3; ZNF93; MED12; HAND2; PHF1; ZNF500; ELF4; L3MBTL1; CBX4; ZNF536; ZBTB7A; HABP4; ZNF426; EZH1; CRTC1; BARX1; AFF2; PPP1R13L; ZNF154; EP300; TBPL1; PROP1; NCOA2; ZNF423; TLX1; TCEA2; YEATS2; FOXO4; ZNF623; FEZF2; CHD2; VENTX; HSF4; APBB1; ZNF217; STAT2; RBPJL; ZNF701; MEIS2; CEBPE; THRB; SUPT7L; ZNF175; HMX1; ZNF155; HIPK2; HOXD1; IRF7; ZFP2; PPARD; ZNF141; NFIX; JAK2; ZBTB44; ETS1; BCL3; CIZ1; ZNF671; SP100; ZSCAN9; EGR1; RCOR3; SOX9; TSC22D3; TULP1; BNC1; LHX3; DCC; TBX6; SUPT3H; ZNF682; ST18; ZNF34; ZNF688; SOX3; GFI1B; DDX17; PRDM14; POU6F2; TBX5; GATA6; CARF; KLF6; ZMYND8; GBX2; SOX12; ZNF257; MAFF; ZNF334; ZNF440; MEF2C; SIM1; RING1; SCAI; ZNF112; CDK9; ZNF43; ZNF611; TGFB1I1; SETDB1; FOXD1; HMBOX1; ZNF304; ZNF573; MXI1; SNAI2; SOX2; WNT4; GLI2; ZNF350; TEAD3; TCF15; SALL2; BTG1; ZNF430; SOX17; E2F5; STAT6; TGFB1; OLIG2; LMCD1; MECP2; ATF3; PLAG1; GRHL2; BCL10; INSM1; FOXN3; NPAS2; KLF11; ZIC3; ZNF44; EHF; PKNOX2; ZHX2; ZSCAN18; JUP; INSR; TERF1; NFATC4; TCF7L1; SOX13; KAT2B; ZNF532; SP140; TBX1; VPS72; ZBTB16; CERS4; TCF7L2; ARNT2; EN1; REL; FLI1; MYRF; TAL1; BCL11A; PBX1; TWIST1; EMX2; ZNF711; BACH1; JUND; HMGA1; NEUROD1; NR1H2; ZNF589; ZNF160; ZFPM2; CITED2; TP63; PDLIM1; CUX2; TULP3; APEX1; TRIM22; MYCN; NFE2; ZBED2; FOXF2; ZFP36L2; ZNF652; ZIC1; TRIB3; BRD4; TRPS1; EYA1; TRIM29; FOXG1; MEIS1; WT1; MAF; TOX; RELB; FOS; OSR2; TXNIP; PLAGL1; DLX5; TBX3; DACH1; ID4
Down-regulation 86 MYCBP; EZH2; TFDP1; CDK2; GTF2A2; RUVBL1; PUF60; MYBL2; ITGB3BP; PARP1; EED; TBP; TCERG1; GMNN; CCNA2; RUVBL2; NUP62; HSF2; PA2G4; FOSL1; TFAM; SUB1; HDAC2; BRCA1; RBM14; CBFB; HMGB1; BCLAF1; CCDC59; CCNC; SFPQ; DNAJC2; DEK; HMGB2; HLTF; BAZ1B; HNRNPD; SSRP1; BMI1; TAF5; TRIM28; XRCC6; PIAS2; ATF1; PTTG1; MED1; FOXM1; UBP1; CBX3; HSBP1; RNF138; RBBP4; RAN; PURA; ENO1; CRY1; CHD1; C1QBP; XBP1; PIR; BLM; HOXC6; CEBPZ; BAZ1A; HMGB3; MTF2; ECD; SAP30; MAGED1; IRX5; HES1; BCL11B; EGR3; TRIP6; WWTR1; HMGN3; SMAD1; NR2F2; SUV39H1; LEF1; AFF1; TOB1; ID2; DNMT3B; ADRB2; BASP1