Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16424 Nvp-bez235 GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 149 TCFL5; HBP1; CALCOCO1; HDAC5; SOX4; CREBL2; FHL2; ZNF117; PBXIP1; ZNF91; MNT; PRDM2; KLF7; ZNF688; ZMIZ1; NAB2; PHF1; INSR; NCOA3; SRCAP; BPTF; AES; ZNF358; EGR1; TSC22D3; ELF4; ZNF654; HOXD1; HINFP; STAT2; ING4; ZNF354A; ZNF768; HMGA2; LZTR1; HOXB13; NFIC; KLF13; ZNF415; PPP1R13L; IRF7; CBX7; CBX4; KLF6; IRF9; PNRC1; FOXN3; MXI1; NR2C1; ZBTB7A; ZKSCAN1; ZNF83; MAFG; EZH1; ZNF665; MED12; RBPJ; ZNF141; PRDM12; L3MBTL1; SUPT3H; MAFF; CARF; ZNF500; ZMYM2; SIN3B; NFE2L1; TSG101; SP110; MED15; APBB1; ST18; PCGF3; ZNF426; PHF20; EPAS1; SOX18; FOXO4; CERS4; ZNF536; BCL3; KDM5B; SALL2; ERBB4; ZNF529; SP100; JUP; ZNF33B; TCEA2; FEZF2; ZNF44; ZNF264; ERBB2; ZBTB16; PAWR; GRHL2; JUND; ZSCAN18; ZNF43; BCL10; ZNF532; CBFA2T3; PEX14; TCEB2; ZFPM2; ZNF423; GATA6; ZNF32; FOXD1; TGFB1I1; NEUROD1; BTG1; INSM1; FLNA; HMBOX1; STAT6; ZMYND8; AEBP1; CUX1; IRF6; HDAC9; VPS72; CITED2; ARID1A; ATF3; PFDN5; ARNT2; TCF7L1; BCL11A; CARHSP1; TAL1; ZNF611; NKX2-1; REL; NFATC4; JUN; FOXG1; PDLIM1; NR1H2; TCF7; RORA; ZNF160; LOXL2; SOX9; TRIB3; ZHX2; RELB; SPIB; MEIS2
Down-regulation 87 MYCBP; PUF60; EZH2; TFDP1; RUVBL1; MYBL2; GTF2A2; CDK2; PARP1; EED; TCERG1; SUB1; GMNN; FOSL1; TBP; NUP62; BRCA1; FOXM1; ITGB3BP; HSF2; SFPQ; CCNA2; C1QBP; DNMT1; BCLAF1; TAF5; SSRP1; RBM14; TFAM; CHAF1B; TGS1; RBBP8; CBFB; XRCC6; ABT1; HLTF; RUVBL2; PA2G4; HMGB1; ING3; PTTG1; HMGB2; UBP1; PRKDC; WDHD1; PPRC1; RAN; CENPF; ORC2; HNRNPD; WDR77; BMI1; NFIL3; NR2F1; BLM; ILF2; DNAJC2; CREG1; BAZ1B; PSMC3IP; SAP30; DEK; DR1; CTR9; MED1; CCNE1; MTF2; BAZ1A; ECD; MNDA; XBP1; HES1; RBBP4; HOXC6; ELF1; GATAD2A; TRRAP; HOXB6; ENO1; PIR; ADRB2; ID2; HMGB3; MSX1; NR2F2; SUV39H1; SSX1