Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16423 Nvp-bez235 GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 177 CALCOCO1; HBP1; PBXIP1; FHL2; HDAC5; IRF9; SOX4; CREBL2; PRDM2; FOXN3; ZNF354A; MNT; ZNF117; AES; CIR1; UBE2B; SRCAP; CBX7; BRWD1; ZNF83; HOXD1; NFATC3; ZNF536; INSR; SPI1; OVOL2; NAB2; SIN3B; NCOA3; NFIC; MEOX2; HMGA2; ING4; ZNF358; CDIP1; SETDB1; ZNF33B; MED12; ZBTB3; TSC22D3; KLF7; CAMTA2; TSHZ2; ZNF573; STAT6; ZNF91; SALL2; ZNF415; KLF13; ATF4; ZNF500; ST18; DLX4; TLE2; ZNF768; ZNF623; ZMYND8; GRHL2; ATF3; BNC1; TWIST1; STAT2; ZNF688; SUPT6H; TEAD3; ZNF112; TGFB1; GLI2; TCF7L1; ZNF665; ZNF667; FOXO4; BTF3; MAFF; EZH1; MEIS2; MYCL; JUP; SOX18; FEZF2; PNRC1; IRF6; TGFB1I1; VPS72; CIZ1; MYRF; FOXD1; ZNF268; ZSCAN18; NCOA2; BAZ2A; ERBB2; SOX9; HESX1; ZNF423; PAWR; ZFHX3; TBX2; SMARCC2; HMBOX1; PFDN5; CARF; CERS4; EP300; SOX3; PCGF3; INSM1; CRYM; ZNF606; ETS1; FLNA; TP63; MECP2; NFATC4; BARX1; REL; ARID5B; IRF7; BCL11A; ZNF331; ARNT2; KLF11; SCAI; NR4A2; JUND; ZHX2; ZNF32; NFE2L1; TFCP2L1; HDAC9; FOXI1; WNT4; KLF6; ZKSCAN1; SIX3; TAL1; TRIB3; OSR2; VDR; HIC2; TCEA2; RBPMS; ZFPM2; MXI1; NPAS2; TULP3; ZIC3; NR4A1; NEUROD1; TRIM22; TERF1; ZNF611; MAF; KLF2; BTG1; KLF5; SIX2; CTBP2; ARID3A; EMX2; NFE2L3; KLF4; DACH1; SOX11; FOXF1; MXD4; FOXG1; GATA6; TOX; TXNIP; NKX2-1; SATB1; TRIM29; THAP11; MEIS1; PBX1; FOS
Down-regulation 88 PUF60; MYCBP; TFDP1; EZH2; PARP1; GTF2A2; HSF2; RUVBL1; NUP62; RUVBL2; SUB1; TCERG1; SSRP1; FOSL1; TBP; DNMT1; TP53; CCNA2; BRCA1; BMI1; EED; WDR77; RBM14; BCLAF1; BAZ1B; ENO1; GMNN; NFIL3; RAN; UBP1; SFPQ; HLTF; PTTG1; PIAS2; C1QBP; ITGB3BP; TFAM; MYBL2; TRIM28; ETV1; PSMC3IP; DNAJC2; BLM; POLR2A; CRY1; ZNF146; RBBP4; DEK; MED1; RBBP7; DR1; XBP1; HNRNPD; PURA; CBFB; STAT3; HMGB1; HMGB2; XRCC6; GATAD2A; SAP30; SMAD5; CTR9; CENPF; BRD8; BAZ1A; FUBP1; NPM1; CTNNB1; BATF3; MTF2; ZBTB18; TRRAP; IRX5; SIAH2; DNAJC1; ECD; HES1; ID2; HMGB3; SUV39H1; LEF1; ASCL1; ETS2; ADRB2; MYB; HOXC6; ID1