Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16388 Plx-4720 GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 67 TOPORS; AR; ZNF222; TAF5; ELF2; HMGA2; NLK; PIAS1; KLF11; ZNF124; TAL1; ZNF12; TLE4; ZNF45; SUB1; E2F8; ZNF180; SALL2; CREB5; RORA; PSPC1; ZNF32; NANOG; BACH1; NCOA2; KAT2B; SALL1; SSX1; PHIP; MTF2; SAP30; HIC2; MED14; JUN; ZNF512B; MYBL1; MAGED1; TGIF1; SOX3; ZFPM2; NFE2L3; SOX11; WT1; TFAP2C; PITX2; DMTF1; CHD9; MEOX1; CUX2; ZNF226; ZBTB20; RBPMS; ZNF423; NKX3-1; MNAT1; ATF3; HHEX; AFF1; FOS; IFI16; PBX1; BASP1; TOB1; HMGN3; MAFB; PBX3; MEIS2
Down-regulation 56 TP53; CRK; FLNA; HSF1; RUVBL1; MYBL2; TGFB1; RUVBL2; CALR; ZNF768; TFDP1; ASH2L; SMARCD2; EPAS1; CNOT3; CAPN15; RELA; TRIM28; STAT5B; MTA1; ERF; PML; ZKSCAN1; GTF2I; EGR1; AES; FOXC1; SMARCB1; PTRF; PPP1R13L; PSMC3; GTF2F1; KDM2A; CBX6; ZBTB38; SF1; MED24; MLXIP; HMGA1; CARM1; MBD2; VDR; TRIM16; ID1; SREBF1; KLF6; PITX1; RBBP4; ENO1; JUND; NR1D2; HOXC6; MXD4; TXNIP; ID3; HOXB2