Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16383 Pf-477736 GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 44 EGR1; TRIM22; CBX4; TSC22D3; CALCOCO1; TOX4; ZMYM2; PNRC1; BCL3; EGR3; FOSL2; HBP1; XBP1; ATF7IP; IRF9; MEOX2; RNF6; SUV39H1; BAZ2B; JUNB; TGIF1; MEOX1; NCOA4; RORA; NR4A2; STAT6; NR4A1; ELF1; TRIB3; CRYM; BACH1; ZBTB1; FOS; SCAND1; NRBF2; TLE4; THAP11; YWHAB; SOX9; FOXG1; EGR2; HOXB2; SATB1; BASP1
Down-regulation 52 MYBL2; NUP62; WHSC1; DNMT1; EZH2; GMNN; PSMC3IP; BRCA1; TAF1A; FOXM1; PRKDC; BLM; ITGB3BP; TTF1; PURA; CCNA2; BAZ1B; HMGB2; CHD7; DNAJC2; CBX3; NRIP1; XRCC6; FUBP1; ZBTB38; CTNNB1; HMGB1; HNRNPD; SOX11; CENPF; KLF5; PTTG1; CSDE1; AEBP1; PTRF; TAL1; ESRRG; MYBL1; NR1D2; GATAD2A; HMGB3; FOXL2; DLX2; HLTF; NKX3-1; PEG3; ATF5; ADRB2; TXNIP; HMGN3; MSX1; LEF1