Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16382 Pf-477736 GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 106 RFX5; TRIM22; HOXB13; EGR1; IRF7; CREBL2; HBP1; CALCOCO1; ZNF195; SP110; ZNF117; HOXD1; HOXD3; PNRC1; CBX4; L3MBTL1; HDAC5; ZNF334; IRF9; ZNF189; MNT; NR4A2; CITED2; RORA; NFKB2; KLF13; CERS4; ZNF467; SIN3B; ZNF3; ATF3; ZNF331; ZNF224; PBXIP1; FOXO4; SOX12; ZFPM2; CDIP1; ATF7IP; ZSCAN31; ZNF112; ZNF268; JUP; KLF6; ZNF43; PAWR; SP100; CBX7; ZNF350; ING4; ZNF91; BTG1; CUX2; ZNF573; ZNF606; TSC22D3; SCAI; PPARGC1A; SALL2; ZMYND8; ZNF248; WNT4; IRF6; FOSL2; ZNF44; ZNF165; ZNF544; ARNT2; TRIM29; ZNF512B; BCL6; NR4A1; MEOX2; BHLHE41; NR3C2; TFAP2C; NFATC4; JUN; KLF4; RUNX3; MNDA; STAT4; CREM; GATA6; MAF; STAT1; NR4A3; PITX2; TOX3; FOSB; MXI1; ADRB2; TOB1; MXD4; KLF10; PBX1; FOS; MEIS1; SMARCA1; HOXB2; HLF; TRIB3; TWIST1; MEIS2; EGR2; BASP1
Down-regulation 46 EZH2; FOSL1; CCNA2; MYBL2; CDK2; HDAC2; PARP1; TCERG1; RUVBL2; HSF2; NUP62; HMGA2; PRKDC; SSRP1; DEK; HLTF; EED; HNRNPD; FOXM1; HOXB7; BAZ1B; NCOA6; BLM; FOXD1; BRCA1; TCEA1; RBM14; NRIP1; HMGB1; RBBP4; BATF3; PTTG1; RBBP8; HMGB2; BMI1; SPEN; SAP30; HSBP1; MSX1; TRRAP; CHD7; HOXC10; DLX5; ZEB2; LEF1; SUV39H1