Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16374 Roscovitine GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 27 HOXA10; BHLHE40; NANOG; SSBP2; ZNF266; RORA; HIC2; CRY1; ZNF32; ZNF217; ZBTB20; ZNF226; NR4A2; AFF1; CUX2; MEOX2; BNC2; STAT1; MYRF; SHOX2; SATB1; SSX1; ARNT2; AEBP1; ZNF423; HOXC6; IKBKAP
Down-regulation 26 UBE2I; EGR1; MTA1; NAB2; EPAS1; ZBTB38; STAT3; NAB1; RUNX1; HEY1; FOXC1; PURA; KLF5; RBBP7; ZNF91; PAX5; ASCL1; PITX1; VPS72; ID1; CHD7; TOX; ID3; SOX9; TRPS1; FOS