Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16373 Roscovitine GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 84 ZNF331; BRWD1; NR1H2; GATA2; KLF11; ZNF74; NANOG; IRF7; SETDB1; NFATC4; NFATC3; ZNF350; NLK; PBXIP1; TFAP2C; ZNF85; ERBB4; HIC2; AR; ELF4; ZNF141; ZMIZ1; MECP2; CUX2; PAWR; SP110; FOXK2; POU5F1B; SALL2; ATF3; NCOA2; HMBOX1; NR5A2; ARNT2; ZNF273; IRF9; SOX18; ZFP36L2; SOX5; PCGF3; ZFPM2; NR4A1; PBX1; CEBPZ; ZNF232; TCEA2; LIN28A; RYBP; MKL2; CREB3L2; ZNF43; SSX1; SOX2; PBX3; SOX3; SOHLH2; WNT4; NR1H4; CERS4; ZNF589; SOX17; IRF8; MYRF; VPS72; TRIB3; MEIS2; HOXD1; OSR2; ZBTB20; ID3; PITX2; TWIST1; ARID5B; ZNF423; TOX; POU2AF1; NKX2-1; ID1; WT1; AEBP1; HOXB2; GATA6; MEIS1; MECOM
Down-regulation 44 MED24; EGR1; HOXC6; FOSL1; RBM14; PITX1; KDM2A; NR2F2; CTNNB1; AES; STAT5B; KLF2; HMGA1; MED1; MTA1; TSC22D2; CTR9; PTTG1; BMI1; YBX1; FOXD1; TRIM16; NR2F1; ENO1; ATF5; JARID2; ZBTB38; HSBP1; SOX9; FOXC1; RBBP4; HOXB7; FLNA; THAP11; PIR; HOXC10; TBL1X; SMAD7; MAF; ZIC1; HMGN3; ADRB2; MAFB; SUV39H1