Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16372 Torin-2 GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 214 CALCOCO1; HBP1; BRWD1; ZNF117; ZNF415; IRF9; HDAC5; ZKSCAN4; ELF4; ZNF667; CAMTA2; MNT; PBXIP1; ZNF362; ZNF74; ZNF239; RSF1; ZBTB3; SETDB1; ZNF500; SALL2; PRDM2; ZNF223; VENTX; ZNF665; CDIP1; CHD2; ZNF835; ZNF345; STAT2; NR5A1; INSR; NR2C1; L3MBTL1; ZNF423; ZNF91; ZNF536; ZNF701; ZNF671; FOXO3; ZNF688; ZNF257; ZFPM2; ZNF573; ZSCAN18; ZNF358; ST18; HMBOX1; KLF7; SPI1; ZNF33B; ZNF768; JUP; FEZF2; ZNF34; NHLH2; HDAC9; SUPT7L; ZNF654; RBPJ; HOXD1; ZNF154; MAFG; KLF13; ZNF141; ZNF217; SRCAP; ZNF682; AFF2; EZH1; BACH2; TRIM22; FOXO4; ZNF264; NFATC1; ZNF354A; ZNF75D; ZNF711; NFATC3; HMGA2; OVOL2; ZNF224; ING4; NCOA2; CBX7; TSC22D3; BPTF; NEUROD1; ZBTB16; CARF; TSG101; SOX4; NCOA3; BNC1; KLF3; RERE; ZIC3; ZNF214; ZNF135; ZNF334; MYRF; SKIL; OLIG2; ZNF93; SCAI; ZNF235; ZNF623; ZNF440; ZNF195; ZNF268; IRF7; SOX3; ERBB2; SALL1; ZNF467; CREB5; ZNF254; JAK2; ZNF532; REL; ZNF350; MED12; PNRC1; HOXB2; NFE2; ZNF225; HHEX; ZNF304; SOX18; ZFHX3; FOXF2; BARX1; MDM2; ZNF611; SMAD3; ZNF165; TAL1; ZBED1; TLE4; ATOH1; SOX2; ERBB4; PCGF3; TOX3; ZNF43; SP100; TFEC; TCEA2; ZNF44; CUX1; NFATC4; SOX11; SOX17; MECP2; LIN28A; CERS6; ARNT2; CUX2; TGFB1; BAZ2B; NKX2-1; ZBED2; PHF20; MXI1; HIRA; BACH1; ID4; MAF; ARID1A; YAP1; PFDN5; KLF4; EP300; ID1; TCF4; FLI1; HIC2; STAT6; SNAI2; STAT4; KDM5B; BCL11A; ARID5B; ZNF160; TCF7L2; ZMYND8; ZNF512B; SMAD7; SATB2; BTG1; HOXB6; SP140L; MYCN; DLX5; VPS72; DMTF1; NRIP1; GATA6; INSM1; PBX1; ATF3; TGFB1I1; ZBTB20; TBX3; APEX1; SCAND1; TRIB3; ID3; KDM5D; FOXF1; PITX2; FOXG1; FOS; RELB
Down-regulation 77 EZH2; MYBL2; TFDP1; MYCBP; GTF2A2; HSF2; ITGB3BP; CCNA2; PUF60; RUVBL1; TCERG1; STAT3; RUVBL2; BRCA1; FOSL1; CHAF1B; NUP62; PARP1; FOXM1; SFPQ; CDK2; BCLAF1; PTTG1; EED; PSMC3IP; PA2G4; RBM14; YEATS4; BLM; CCDC59; PURA; TFAM; MED6; HOXC6; SUB1; HMGB1; PSMC3; NPM1; CENPF; ENO1; HMGB2; CBFB; PAX5; PIR; NR2F2; MED1; CCNC; MED7; FUBP1; TRIM28; BMI1; BATF3; SMARCE1; HLTF; CRY1; DEK; RNF6; RAN; NAB1; ACTL6A; SAP30; XBP1; RBBP7; TOB1; PMS1; PITX1; ECD; CTR9; WWTR1; RUNX3; IRX5; MTF2; STAT1; HOXC10; DNMT3B; SUV39H1; HMGN3