Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16370 Torin-2 GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 101 SOX4; FHL2; TSC22D3; HBP1; HDAC5; HOXB13; PBXIP1; BPTF; FOXO3; MNT; ZNF415; CALCOCO1; ZNF117; IRF7; KLF6; KLF7; CREBL2; PNRC1; IRF9; IRF6; CDK7; ZNF358; PPP1R13L; ERBB2; ATF4; JUP; TRIM22; MAFG; CDIP1; ZNF768; HIVEP1; ZNF33B; RBPJ; OVOL2; HMGA2; TSG101; ZNF500; PAWR; RCOR3; NCOA2; HMBOX1; ZNF665; ZBTB43; ZNF573; ZNF623; ZNF83; SUPT3H; TCF7L1; ZSCAN18; HOXD1; ZNF91; GRHL2; NCOR2; PDLIM1; ZKSCAN1; EMX2; TCEA2; PHF20; SALL2; ZNF264; CITED2; ZNF281; MAF; ZBTB16; NFE2L1; BACH1; EP300; RSF1; TGFB1I1; HDAC9; CUX1; KLF11; KDM5B; APEX1; BCL11A; ZFP36L2; TFEC; CHD9; FOXG1; ZNF512B; ZNF160; ATF3; BTG1; KLF4; SNAI2; ARNT2; TCF7; JUN; HOXB2; GATA6; TRIM29; AHR; TRPS1; MXD4; TBX3; SMARCA1; TXNIP; BASP1; ID4; ZIC1; FOS
Down-regulation 68 MYCBP; TFDP1; CDK2; MYBL2; EZH2; GTF2A2; RUVBL1; PARP1; FOSL1; SUB1; HSF2; ITGB3BP; TBP; TLE1; CCNA2; PA2G4; EED; RFX5; GABPB1; TFAM; HMGB1; RBL1; ING3; BRCA1; RUVBL2; BLM; WDR77; HMGB2; FOXM1; NUP62; PRKDC; C1QBP; RBBP7; HLTF; CHD1; RNF6; ETS1; ELF5; PTTG1; SFPQ; PSMC3IP; CBFB; NR2F2; RNF138; BCLAF1; PURA; HNRNPD; ZNF267; CHD7; HOXB7; DEK; MAGED1; BMI1; MTF2; MYBL1; TOB1; NRIP1; PMS1; CEBPZ; PIR; ELF1; SAP30; BCL11B; BAZ1A; LEF1; SUV39H1; ADRB2; E2F2