Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16369 Torin-2 GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 171 CALCOCO1; HBP1; HDAC5; SOX4; TSC22D3; ZNF688; SRCAP; IRF9; FHL2; PBXIP1; ATF4; ZNF500; MNT; FOXO3; ZNF117; HINFP; STAT2; LZTR1; PHF1; NCOA3; BRWD1; HOXD1; HMGXB3; CREBL2; FOXO4; ZNF224; ERBB4; ZKSCAN4; SIX6; ZNF33B; IRF7; GON4L; ZNF768; ELF4; INSR; NAB2; FOXN3; KLF7; CAMTA2; KLF13; PNRC1; AFF2; YEATS2; ZNF217; SALL2; CBFA2T2; BPTF; NFATC3; PAWR; ZNF91; IRF6; ZNF358; GTF2IRD1; SPI1; ZBTB16; CIR1; L3MBTL1; ZNF444; HDAC6; SP100; ZNF536; ERBB2; PCGF3; ING4; SETDB1; MAFG; EZH1; ZKSCAN1; SMAD3; UBE2B; RING1; EP300; ZNF665; TEAD3; TSG101; ZNF264; SIN3B; NFE2L1; HMBOX1; ZNF12; REL; ZNF34; TCEA2; SUPT3H; ZSCAN9; CDIP1; BTG1; MXI1; ST18; ZNF423; CARF; MED12; PLAG1; FEZF2; ZNF83; ZNF345; SCAI; ZNF415; ATF3; ZNF112; LDB1; STAT6; DDIT3; MAFF; NPAS2; ZNF623; ZNF611; NFATC4; SP110; SOX2; ZNF467; ZNF419; VPS72; SOX13; KLF11; ZBTB43; DAXX; ID4; DLX5; ARID1A; ARID3B; ZSCAN18; BAZ2B; BHLHE41; ZIC3; BACH1; ARNT2; TRIM22; ZNF160; MECP2; ZNF44; JUND; SOX17; SOX3; ZNF165; HDAC9; HTATIP2; ZNF93; TGFB1I1; BRD4; TBX1; GATA6; ZFPM2; ZNF430; CERS4; KLF6; NKX2-1; SP140L; BCL6; POU2AF1; NEUROD1; TRIB3; ZNF652; ZHX2; FLNA; LMCD1; MEIS2; ZMYND8; MYBL1; TXNIP; ZNF589; RORA; FOXF2; ZNF512B; PITX2; AHR; SMARCA1; FOS; RELB; CREG1; MEIS1
Down-regulation 94 MYCBP; TFDP1; EZH2; FOSL1; TCERG1; SUB1; RUVBL1; PARP1; MYBL2; EED; GTF2A2; TBP; PUF60; CDK2; HDAC2; ITGB3BP; RUVBL2; CCNA2; SSRP1; NUP62; PA2G4; CBFB; HMGB2; PTTG1; SFPQ; BRCA1; RBM14; BCLAF1; HMGB1; ATF1; ETV1; TAF5; GMNN; HLTF; DEK; HNRNPD; C1QBP; MED1; RAN; RBBP4; TBPL1; RBBP7; TOPORS; ING2; TRIM28; SMARCA5; TFAM; ECD; PITX1; FOXM1; CENPF; CCDC59; HDAC1; LEF1; CALR; NAB1; SMARCA2; ILF2; CRY1; NPAT; CBX5; CEBPZ; HSBP1; MTDH; PURA; SAP30; BMI1; HOXA10; TSC22D2; CTR9; ADRB2; PSIP1; CHD7; HES1; ENO1; NPM1; MTF2; NR2F2; HOXB7; BAZ1A; PIR; EGR3; ELK3; BCL11B; HMGB3; IRX5; ZEB2; SUV39H1; HOXC6; ID1; POU4F1; MSX1; PEG3; EGR2