Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16367 Torin-2 GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 302 NFATC3; HBP1; CALCOCO1; TSC22D3; HDAC5; CIR1; ATF4; KLF13; TBX21; SOX4; HOXB1; FOXO4; MXI1; NR5A1; GON4L; STAT2; CRX; ZNF688; ZNF76; IRF7; PRDM2; CBFA2T2; ING4; ZNF768; YEATS2; SPI1; ZNF117; IRF9; SRCAP; HDAC6; HINFP; PBXIP1; MZF1; NCOA3; EZH1; ZBTB48; PNRC1; MAFK; FOXO3; ZNF506; BTG1; CAMTA2; DYRK1B; ESR2; CEBPD; DDIT3; CEBPE; KLF6; ZBTB25; MED12; KLF7; E2F2; GTF2IRD1; PRDM8; CBX4; INSM1; ZNF358; MAPK8IP1; MEF2D; ZNF224; APBB1; ZNF654; GBX1; IKZF4; ZNF446; RORC; LZTR1; ZNF500; HEYL; ZSCAN16; ZNF221; NEUROG3; MAFG; PRDM12; ZNF175; PRDM4; ALX3; EMX1; ZNF536; ZNF83; THRB; CDIP1; ZBTB17; TBX4; ERBB2; HMG20B; PAX2; ZNF23; ZNF133; GBX2; PSPC1; ETV2; MNT; INSR; ZNF217; NR2C1; ZNF33B; ZKSCAN1; FOXN3; CERS4; MAML3; ZNF671; PPP1R13L; NEUROD1; PHF1; EP300; MXD3; ZNF205; SIX6; KDM4C; HOXB13; NKX6-1; SP100; JUP; KAT2B; ARNTL; POU3F3; TULP1; CBX7; GCM1; MAFF; TONSL; DMTF1; CDX4; TERF2; SCRT1; ZBTB43; SIRT7; CARF; ZNF337; RNF10; HIF3A; TBX6; E4F1; TLX1; TAF6L; IRF8; HSF4; ELF4; ZSCAN2; L3MBTL1; BCL3; ZNF91; RCOR3; SNAI1; RFX1; NPAS1; UIMC1; LPIN2; SIX5; EVX1; TRIP4; PRDM9; MLLT1; ZNF354A; ZBTB16; NFIX; MLLT10; POU6F2; NAB2; HOXD12; NEUROG2; ERBB4; ZNF532; ARID5A; PAWR; ZNF155; FEZF2; SIN3B; CIZ1; ESRRB; ZNF112; UBE2B; TSG101; SMARCC2; ZSCAN9; SOX12; NPAS2; ZNF573; ZMYM2; LMO1; NHLH1; FOXH1; ZXDC; ZNF34; ZNF440; ATF3; PHF20; HESX1; DDX17; ZBTB44; HNF4A; GSC2; NCOA2; ZNF75D; SOX3; MYRF; ZNF334; KLF11; TAL1; ZZZ3; ZNF682; ZBTB20; FOSL2; LHX3; HMBOX1; BPTF; CITED2; HTATIP2; ELF3; SUPT6H; SCAI; ZNF611; ZNF415; AES; CRYM; BANP; CIITA; SETDB1; ZNF345; JUND; POU2F2; ZNF350; KLF3; ZNF93; PCGF3; HOXD1; TCF15; NFE2L1; MDM4; WNT4; ONECUT2; ELF5; IRF6; ZNF248; KLF5; ZNF419; ABL1; ZMYND8; NCOA6; ZNF467; ATOH1; DLX4; ZNF44; BACH1; DEAF1; BRD3; ZNF606; LMCD1; FUBP1; TGFB1I1; MEOX2; DLX5; PAX6; SP140; ARNT2; SOX2; FOXO1; ZNF43; NR1I2; NFIB; PHIP; PITX2; ZNF160; ST18; MEOX1; RORA; CBFA2T3; NFATC4; KDM5A; ANKRD1; NR1H4; STAT4; MAF; ZIC3; HDAC9; MED13; ZNF423; BRD4; TULP3; TLE1; BCL11A; KDM5B; KDM5D; CREB3L2; ZSCAN18; SMARCA1; ASCL1; EYA1; FOS; PBX1; MXD4; CTBP2; DACH1; SOX17; SPIB; MEIS1; BASP1; GATA6; CREG1; ZIC1; TOX3
Down-regulation 109 MYCBP; GTF2A2; FOSL1; TFDP1; PARP1; RUVBL1; MYBL2; CDK2; EGR1; HDAC2; TFAM; RUVBL2; CCNA2; EZH2; SUB1; PUF60; GMNN; C1QBP; PA2G4; PCBD1; NUP62; SFPQ; TRIM28; CBFB; DRAP1; SSRP1; LEF1; DNMT1; BRCA1; EED; BMI1; ILF2; MED6; ITGB3BP; RBM14; WDR77; RRN3; BCLAF1; SMARCA5; RNF138; NFKB1; PPRC1; PTTG1; C1D; HMGB2; HNRNPD; THAP1; MED21; ATF1; PLAGL2; CEBPZ; RBBP7; DEK; UBP1; TRIM27; MAGED1; HLTF; ABT1; TAF9; HMGB1; FOXM1; CTNNB1; ZNF200; RAN; ADRB2; STAT3; XRCC6; CCDC59; WDHD1; TEAD4; CHD1; ID1; MTDH; SMARCD2; SMAD1; BAZ1A; HOXA5; NR2F2; HOXB7; CCNE1; PIR; HES1; SIAH2; EGR3; HMGA1; BLM; ENO1; JARID2; LOXL2; PSIP1; HEY1; MKL2; ID3; NPM1; SATB2; SPEN; MTF2; IRX5; HMGB3; BCL11B; ELK3; TRIP6; WWTR1; EGR2; PITX1; ID4; MYB; AEBP1; SUV39H1