Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16366 Pelitinib GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 223 FOXO3; IRF9; PBXIP1; CALCOCO1; TSC22D3; DYRK1B; TRIM22; ZNF768; CSDC2; MKL1; HDAC5; HBP1; PRDM2; ID2; ELF4; ZNF688; TP53; TSHZ2; MNT; FOXO4; ZBTB7A; PNRC1; CBX7; SREBF2; ING4; IRF6; MTF1; EMX2; MEIS1; KDM4A; ATF3; ZNF224; BCL6; AES; CREBL2; RARB; IRF1; ZBTB48; ZNF665; ZMYND8; NR5A1; ZKSCAN4; ETV6; YEATS2; NFKBIA; ZNF44; THRB; SOX4; AFF2; SUPT7L; ELF3; L3MBTL1; ZSCAN31; WNT4; ZNF536; ERBB4; CUX1; SALL2; CIR1; HOXB5; CHD3; STAT2; NFIC; MXI1; CBX4; ESRRA; SRCAP; INSR; ZNF33B; ZNF467; FOXN3; TFAP2A; FOSL2; ZNF415; ZNF117; ZNF177; SIRT7; CDIP1; BTG1; RARG; TEAD3; KLF3; ZNF358; HMBOX1; TCF25; ZNF136; ZNF112; HEY1; NR4A2; ZNF266; HOXD1; NHLH2; EHF; ZNF573; OVOL2; HINFP; UBE2B; PEG3; NFIX; OSR2; SIAH2; ZNF345; ZNF268; ZNF165; FOXO1; RREB1; SOX12; ZNF140; SIN3B; ZFPM2; MEIS2; ZNF83; RING1; BPTF; ZNF426; ZNF500; E2F5; EPAS1; ZKSCAN1; SOX17; ZNF91; SUPT6H; ZNF304; NFE2L2; MDM2; PBX1; TGIF2; TFCP2L1; MECP2; ARL2BP; CARF; ID1; MNDA; ZNF141; RBL2; NFE2L1; HESX1; SOX3; MYRF; NFE2; IRF7; ZNF711; SSBP2; MYCL; TXNIP; NCOA2; TCF15; LPIN2; MECOM; ZNF160; EZH1; ZNF350; ZIC1; SP110; ZNF606; ERBB2; PCGF3; NEUROD1; SP100; MEOX2; GATA6; TRIM29; TCEA2; JAK2; HIC2; ZNF652; PAWR; BCL11A; ZNF611; ZNF394; ESR1; CRYM; CBFA2T3; BRD4; ZNF264; RSF1; ZNF43; CERS4; ZNF93; KLF4; TP63; SREBF1; EP300; HOXB2; TRPS1; TWIST1; VGLL1; HDAC9; DAXX; KLF5; SNAI2; ARNT2; MAF; TLE1; SOX2; ZBTB16; BRD2; HOXB6; DLX5; ZNF512B; SPDEF; REL; MXD4; TFEC; JUND; TRIM16; TRIM24; MYCN; PAX6; TOB1; ARID5B; ZSCAN18; INSM1; ID3; CREG1; REPIN1; ZNF423; FOSB; CTBP2; DACH1; ASCL1; WT1; FOS
Down-regulation 104 PUF60; FOSL1; HMGA2; EZH2; PDLIM1; CCNA2; MYBL2; ABL1; TCERG1; EGR1; FHL2; FOXM1; RUVBL2; PTTG1; HSF2; NUP62; GMNN; SSRP1; DRAP1; BMI1; CENPF; PMF1; EED; HNRNPD; CHAF1B; HMGB2; ETV1; ZNF143; SUB1; MYCBP; TTF1; TRIM28; CDK2; RUVBL1; BAZ1B; BRCA1; MED27; BRIP1; PARP1; HMGA1; BCLAF1; PA2G4; ITGB3BP; WHSC1; RBL1; WDHD1; EGR3; MTF2; TAF1A; CBX5; BATF3; PSMC3; C1D; SATB2; RBM14; PSMC3IP; YEATS4; NFKB1; CBFB; BLM; DEK; CRY1; NELFB; RAD21; SFPQ; HMGB1; RAN; DR1; RBPMS; ETS1; UBE2I; ILF2; TFAM; RNF4; ING3; ETV4; EDF1; ARNTL; ELK3; NFIB; NPM1; HLTF; RBBP8; XBP1; HHEX; HOXC10; AGO2; SAP30; FOXD1; PTRF; MYB; WWTR1; NRIP1; BAZ1A; CEBPZ; ENO1; AFF1; SUV39H1; SOX9; MYBL1; PPARG; NKX3-1; KDM5D; SATB1