Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16364 Pelitinib GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 240 CALCOCO1; TSC22D3; PRDM2; PBXIP1; HBP1; HDAC5; ZNF768; MZF1; FOXO3; CREBL2; CIR1; BPTF; RARG; ING4; ZNF83; ELF3; DYRK1B; ZNF358; CBX4; NCOA2; ZNF274; ZKSCAN4; JUP; TSHZ2; NFATC3; L3MBTL1; MKL1; IRF9; ZNF688; HOXB1; CSDC2; SETDB1; ZBTB48; TRIM29; ATF4; ZNF117; BCL6; BRWD1; ERBB4; SRCAP; TRAK1; CBFA2T2; ZNF444; ZNF467; NFIL3; KAT5; FOSL2; SUPT6H; MEIS2; HDAC6; PPARG; ZNF112; ELF4; THRA; ZNF174; NR3C1; SUPT7L; NR5A1; ZBTB3; NCOA3; ZMIZ1; PNRC1; RNF10; EZH1; TRPS1; SALL2; ZNF33B; MAML3; MED12; RARB; STAT5A; MYRF; SPI1; MNDA; ID1; NFKBIA; VENTX; ZNF652; NFE2L2; MECOM; FOXO4; ID2; LPIN2; ZNF264; PBX1; TCEA2; MECP2; MEIS1; SIRT7; YEATS2; SUPT3H; TRIM22; ZNF667; ZNF133; TRIM16; BCL11A; VGLL1; ZNF337; ZNF415; HDAC9; TFAP2A; FOXO1; HSF4; ZNF623; ATF3; TFEB; PAX9; TFEC; KAT2B; DDX17; STAT2; ZNF223; DDIT3; ZMYM2; CARF; RBFOX2; AES; TEAD3; SOX2; ZNF304; JAK2; PRDM14; ZNF711; MEN1; ZNF224; SUPT4H1; ZNF248; OVOL2; RCOR3; CIITA; CBX7; BARX1; ZNF268; BAZ2B; KLF11; LYL1; ZNF665; KLF3; SNAI2; WWC1; HEY1; ZNF532; SOX3; ZNF423; ZSCAN31; MXI1; ZFPM2; ZNF426; NFE2L1; BATF; HIVEP1; SP140; RXRA; BTG1; FUBP1; TLE4; SIX3; NAB1; ZNF140; KLF4; ST18; SREBF1; ZNF580; PEG3; ZNF606; NFATC4; ZNF217; CRYM; NFE2; EMX2; TP63; NR1H4; PEX14; TCEB2; FOXN3; ELF5; ERBB2; INSM1; MED13; TOB1; NPAS2; TGIF1; WNT4; SOX17; CREB5; VPS72; KAT2A; TXNIP; SMARCD3; FOXF2; OSR2; HLF; TWIST1; NR1H3; ARNT2; FOSB; PLAGL1; ARID5B; CERS4; TLE1; ZBTB16; CHD9; ZNF131; FOXC1; KLF5; GATA6; SP140L; ZNF611; SMAD6; TRIB3; TCF7L1; NFAT5; TBX1; DLX5; JUNB; PHF20; SIX2; MKL2; PHIP; REL; FOXG1; BNC2; PAX6; MAF; HIC2; ZNF91; ZMYND8; ZNF512B; MYCN; LITAF; HMGN3; ID4; ZNF589; KLF10; CREG1; ZHX2; AHR; WT1; TOX3; BASP1
Down-regulation 105 CRK; FOSL1; HMGA2; EZH2; PDLIM1; CDK2; CCNA2; DRAP1; FHL2; MYBL2; PTTG1; PA2G4; MYCBP; PUF60; FOXM1; TFDP1; TCERG1; GMNN; WHSC1; HNRNPD; BRCA1; DNMT1; RUVBL1; NUP62; NPM1; PARP1; EED; TOPORS; RHOA; CTR9; MED6; HSF2; CRY1; CENPF; HMGA1; C1D; SUB1; RUVBL2; TRIM28; SATB2; PURA; GABPB1; SSRP1; PPRC1; C1QBP; CBFB; ABT1; HMGB2; ETV1; PSMC3IP; NOC2L; RBM14; SFPQ; ITGB3BP; RNF4; TTF1; YWHAB; SMARCA5; HMGB1; DR1; FOXD1; RAN; UBP1; BCLAF1; MTF2; TFAM; ING2; HMGB3; WDHD1; KLF6; GATAD2A; RBBP8; ING3; HLTF; ZNF281; ETV4; ELK3; BMI1; ZNF22; TSC22D2; NR2F6; EGR3; HOXB7; ENO1; BATF3; HSBP1; MSX1; HOXC10; PSIP1; BAZ1A; SAP30; CEBPZ; ECD; CHD7; SUV39H1; HOXC6; ETV5; IRX5; PBX3; MYB; MNAT1; BRD4; WWTR1; CTBP2; NR2F2