Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16363 Pelitinib GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 277 TSC22D3; IRF9; GLI2; HDAC5; ZKSCAN4; MKL1; SALL2; ERBB4; NFATC3; ELF4; ZNF331; ZNF768; BRF2; ZNF688; NR5A1; HIF3A; PRDM2; ZNF264; ZFPM2; EMX2; CALCOCO1; CSDC2; CREBL2; CIR1; ZBTB3; ZNF665; ZNF268; ZNF117; ZNF667; ZNF44; ZNF500; TRIM22; MEIS1; HBP1; BRWD1; ZNF444; SUPT7L; ZNF423; BPTF; NEUROG1; PBXIP1; ARHGAP35; ATF3; ELF3; ZNF358; NCOA3; NFE2L1; FOXO3; TFAP2A; NFIX; ZNF224; IRF6; HOXB5; CDIP1; FOXO4; TFDP2; TP73; MEIS2; PRDM12; ING4; ZNF467; ZNF195; ZNF512B; KAT2B; ZNF223; TCF4; HINFP; AFF2; CBX7; ZNF222; PNRC1; ZNF85; VENTX; ZNF34; RSF1; HLX; ZNF75D; ZNF91; SOX18; THRB; MYF5; EHMT1; ZNF711; ZNF43; TSHZ2; ZNF354A; MXI1; CREB3L1; GRHL2; KDM4A; ZNF682; ZNF611; ZSCAN18; MECP2; ZNF345; FOXN3; OVOL2; RING1; STAT2; ZNF257; ZNF573; EVX1; GATA2; GATA6; YEATS2; RARG; BNC2; TRIM29; ZBTB44; PKNOX2; AR; TAF6L; EMX1; SETDB1; NLK; CBFA2T2; SIX2; TCEA1; TRIM16; CUX1; TEAD3; SOX2; EPAS1; WT1; BARX1; ATF4; IRF7; NHLH2; ZNF623; LPIN2; POU2F1; TLE2; WWC1; NFATC4; BCL6; MECOM; NR1I3; AES; ZHX2; ZNF112; PBX1; THRA; NFE2; MED12; SCAI; MYRF; ZSCAN31; RFX7; BCL11A; BCL3; ZNF426; ZNF350; NCOA2; EHF; TCEA2; ZNF141; NANOG; ZNF33B; SUPT6H; WNT4; CUX2; KLF13; SOX17; BACH2; L3MBTL1; CARF; ZNF329; ZNF254; ZNF83; TGIF2; ZNF606; MEF2C; ZNF136; FEZF2; HEY1; TOX; SSBP2; LMCD1; CERS4; BAZ2B; TWIST1; DBP; ZNF652; PAWR; NEUROD1; HIVEP1; HESX1; ZNF304; RXRA; ZNF415; HMBOX1; HIRA; ZNF160; OSR2; JUP; TGIF1; ID1; EZH1; ZNF225; ZKSCAN7; ID3; PCGF3; SOX3; NFE2L2; ESR1; HOXB2; ZFHX3; ZNF419; TRIB3; TFAP2C; ATF2; ZBTB20; SOX13; TBX1; NCOR2; TCF7L2; TFEC; RUNX1; TCF15; CHD9; ARNT2; NR4A2; HOXB6; ZIC3; CBFA2T3; POU2F2; PHIP; FOSB; ERBB2; ST18; E2F5; PDLIM1; ZNF12; AHR; FOSL2; HDAC9; ZNF165; ZNF589; TLE4; NR5A2; MNDA; VPS72; ARID5B; ID2; INSM1; TAL1; ZMYND8; MYCL; MEOX2; NCOA1; EP300; ZNF544; KLF4; HLF; EYA2; ELF5; BTG1; POU2AF1; ZNF721; SPDEF; PIR; SMAD1; ZIC1; HMGN3; CTBP2; AEBP1; ID4; PEG3; REPIN1; TP63; MXD4; TCF7; BASP1; CREG1; FOS; CREB1; E2F2
Down-regulation 97 FOSL1; HMGA2; FHL2; MYCBP; EZH2; EGR1; PUF60; TFDP1; CDK2; RHOA; CCNA2; MYC; ITGB3BP; CBFB; GTF2A2; TCERG1; HDAC2; SSRP1; DRAP1; RUVBL1; PA2G4; BMI1; RUVBL2; BRCA1; PARP1; C1QBP; EED; RBL1; CALR; CENPF; CHAF1B; BCLAF1; EGR3; MAFF; GABPB1; SUB1; MYBL2; HOXC6; HMGA1; ZBTB38; RAN; PSMC3IP; YEATS4; TSC22D2; SATB2; PTTG1; ETV1; C1D; CHD1; ELK3; WWTR1; GMNN; RBM14; HNRNPD; TBPL1; TFAM; NPM1; FOXM1; BAZ1A; HLTF; TRIM28; PURA; SFPQ; ING3; HMGB1; BATF3; PPRC1; PRKDC; WDHD1; RBBP4; DEK; TGFB1; ARNTL; ETV4; SAFB2; YWHAB; AATF; JUNB; FOXD1; HOXC10; SMARCE1; HSBP1; HMGB2; NR2F2; ELF1; NKX2-2; ECD; NR2F1; SUV39H1; SOX9; TBX3; KDM5D; NKX3-1; IKBKAP; POU4F1; MSX1; EGR2