Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16355 Azd-6482 GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 195 NR3C1; ZFPM2; IRF9; CALCOCO1; PRDM2; ZNF117; SALL2; HBP1; BRWD1; ZNF331; NFATC3; NANOG; FOXN3; NCOA2; BNC2; PRDM14; HOXB1; HINFP; ZNF33B; ZNF154; ZNF85; ZNF354A; ZKSCAN4; ZNF345; TCEA2; ZBTB3; BACH2; ZNF217; ZNF175; BCL11A; ZNF75D; CREBL2; SOX2; ZNF223; GLI2; VENTX; NFATC4; KAT2B; TLE4; ZNF195; TSC22D3; ZNF257; CBFA2T2; L3MBTL1; TFAP2A; ZNF141; NLK; LHX3; ZNF43; PBX3; ZSCAN16; THRB; PIAS1; TCF4; ZNF423; ZNF235; ZMIZ1; ZBTB44; ZNF665; ZNF124; TCF7L2; PAWR; BNC1; ZNF268; KLF11; ZNF682; ZNF711; ZNF573; ERBB4; AR; ZNF415; HOXB5; BPTF; NR0B2; TGIF1; KLF13; MEIS2; ZNF467; ZNF500; PRDM10; CUX2; ZNF667; TRIM22; SOX3; CDIP1; POU5F1B; RERE; HOXB2; CBX7; ZHX2; ARNT2; BARX1; ZNF224; ZIC3; PNRC1; ZSCAN18; IRF6; HESX1; SMAD3; TCF7L1; ZNF180; MECP2; ZBTB20; ZNF273; ZNF529; NR5A2; NR4A2; ZNF350; MXI1; ING4; HOXD1; EZH1; ZEB1; PKNOX2; SOX13; PCGF3; PHIP; HIVEP1; SP100; E2F8; ZNF623; ARID5B; NFE2L3; SOX11; USP21; SOX18; ZNF232; ZNF512B; BACH1; TFAP2C; SPDEF; ARID3B; CHD9; ZNF589; ID4; RSF1; ZNF165; TP63; LIN28A; ZNF611; CERS4; PBX1; WT1; TCF21; ZNF93; TRIB3; CRYM; JAK2; ZNF12; IRF8; ARID1A; TULP3; FOXO1; ZNF544; MEIS1; ZFP36L2; HMBOX1; INSR; CREB3L2; FLI1; MYRF; KLF7; ID3; GATA6; HDAC9; MEOX2; BTG1; ST18; E2F5; MYCL; MNDA; CBFA2T3; ZBED2; AEBP1; WNT4; POU2AF1; HIC2; ZSCAN31; VPS72; FOXF2; MED13; SOHLH2; SOX17; SSX1; ATF3; TRIM29; ZNF91; DLX5; BASP1; NKX2-1; FOXF1; SPIB; CREB1; ID1; FOS
Down-regulation 63 FOSL1; PUF60; FOXJ3; FLNA; RUVBL1; EGR1; TRIM28; EDF1; DRAP1; RUVBL2; SUB1; NUP62; BMI1; BRPF1; PA2G4; PITX1; NELFB; MED1; DNAJC2; MTA1; HLTF; MED6; SMARCD2; ELF1; HOXC6; MYBL2; POLR2A; CBFB; BATF3; BCLAF1; SMARCE1; AATF; RBM14; ENO1; CARM1; RBBP7; PIR; CTNNB1; HDAC1; NPM1; XBP1; IRX5; NR2F2; RBBP4; CTR9; HOXC10; SREBF1; SATB2; FOXC1; CALR; MSX1; LEF1; ZBTB38; EYA2; FOSL2; JARID2; EGR3; BRD2; NKX3-1; ELK3; ADRB2; SUV39H1; KDM5D