Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16348 Azd-8330 GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 391 CALCOCO1; FOXO3; IRF6; HBP1; ZNF224; ZKSCAN4; ZNF264; CREBL2; JUP; IRF9; HOXB1; CSDC2; ZNF117; ZNF124; NR5A1; PNRC1; ZKSCAN1; ZNF665; ZNF669; SUPT7L; PRDM2; CDIP1; BRWD1; AFF2; CBX7; TRIM22; DYRK1B; VENTX; ZNF667; ZNF91; ZBTB44; ZNF221; ZNF345; TSC22D3; CHD2; NEUROG1; ZNF362; ZNF257; NFATC3; THRB; HINFP; SRCAP; ZNF223; STAT2; KLF13; PBXIP1; ZBTB3; ELF3; ZNF816; ZNF219; REL; ZNF426; MKL1; GRHL2; ZNF331; ALX3; ZSCAN16; ZNF573; L3MBTL1; MAML3; ZNF136; ZSCAN9; MDM4; ZNF701; MEF2C; RFX5; ZNF768; TBX4; TRIM33; ARID5A; ZNF44; ZNF177; CARF; SPI1; TULP2; ZNF76; ZNF500; ZNF93; ING4; TAF6L; HDAC5; ZNF611; RING1; ZNF471; ZNF195; ZBTB16; CRX; ZNF682; ZNF350; NR2C1; PRDM10; ZNF652; ZNF835; ZNF688; HMGXB3; MZF1; ZNF112; ZKSCAN7; ZNF444; PRDM14; BPTF; KLF1; ZNF250; ZNF132; TRIM29; ZNF415; MAF; TERF2; PRDM12; ZNF85; GLI2; ZSCAN32; ZNF154; ZNF33B; ZNF571; KLF11; HDAC9; ST18; ZNF268; TAF1; ZNF208; ONECUT1; SCAI; ZNF358; INSM1; NCOA2; RARG; TP73; SALL2; EMX1; CCNH; ZNF536; HESX1; ZIC4; RARB; TP63; HEYL; RFX1; ZNF75D; ZNF671; JAK2; ZNF430; CERS4; NR6A1; SOX3; LHX3; RBBP5; ASCL3; BCL6; TFAP2A; ZNF140; MED31; ZNF141; GON4L; FOXH1; NHLH2; KAT2B; TSHZ2; NANOG; ZNF337; ARHGAP35; ZFPM2; NFATC4; PRDM9; ZMIZ1; ELF4; FOXN3; TULP1; CIR1; BNC2; BACH2; ZNF606; ZNF286A; SOX4; PPARA; MXI1; TLX2; MED25; OSR2; RCOR3; ETV3; ZNF675; IRX4; FOXE3; EHF; BCL11A; RSF1; ZNF423; ZNF334; MAPK8IP1; AES; WNT4; AR; ZHX2; POU3F3; MNDA; PROP1; TAF4B; NR0B2; VGLL1; ZNF304; MEIS2; CBX4; CEBPE; ASH1L; ZFHX3; BRDT; ZNF3; ZNF695; ZNF510; DLX4; ZNF225; FOSL2; ZNF749; ZKSCAN8; SOX18; EP300; SREBF2; ZNF43; CUX1; NFIX; ESRRB; ZNF135; MEIS1; LMCD1; TBX5; ZNF83; ZNF160; SOX12; IRF7; CIITA; ZNF780B; SOX2; ZNF235; PRRX1; SPDEF; ZNF623; SP4; MECP2; ZNF81; ZNF155; MAK; TEAD3; NEUROD1; BTG1; ZNF165; ZMYM2; ZNF440; CBFA2T3; RFX3; FEZF2; TRIM16; SP140L; ZNF529; ZNF467; ZSCAN31; SKIL; HOXB5; SOX17; MDM2; GCM1; MEN1; TLE4; TBX6; PRDM1; THAP10; PIAS4; NCOA3; ZNF180; HNF4G; ZNF239; ZNF492; HMBOX1; CUX2; FOXF2; THRA; CREB5; ZNF253; ZIC3; EZH1; MYCL; ID4; NEUROG2; PCGF3; NFAT5; MYRF; NR1H4; FOXF1; FOXI1; LPIN2; LIN28A; SOX5; KLF3; NR1H2; SUPT3H; NR5A2; HIPK1; ZSCAN18; SIM1; RXRA; ATF3; POU2F1; EPAS1; POU5F1B; BARX1; ACTL6B; ZNF544; ESRRG; TCF7L2; ZNF589; ARNT2; ATOH1; ZNF217; BHLHE41; ZNF254; STAT4; ZNF419; HIC2; ZNF711; TBX1; SNAI2; LITAF; GATA6; SOX13; ERBB4; ISL1; ARID5B; ID2; PKNOX2; TRIB3; FHL5; SSBP3; HOXD1; ZNF232; TGIF2; SP2; TFEC; TOX; ZNF394; ZNF512B; TCF4; HLX; INSR; MEOX1; BAZ2B; DLX5; PDLIM1; HOXB2; FOXO1; KLF4; TFAP2C; LYL1; TCF7L1; ZBED2; ZBTB20; DAXX; E2F5; WT1; VDR; PBX1; ID3; SALL1; NFE2; SMAD6; SSBP2; IRF8; MED13; HEY1; TRPS1; TCF21; MYCN; ZIC1; TULP3; HEY2; VPS72; DACH1; IFI16; CD3D; SHOX2; TCF7; PHIP; MAFB; AHR; GATA2; AEBP1; POU2AF1; MXD4; ESR1; PEG3; KDM5D; E2F2
Down-regulation 102 FOSL1; HMGA2; CCNA2; PUF60; EZH2; MYCBP; TCERG1; RHOA; EGR1; SUB1; HMGB2; MYC; NUP62; BCLAF1; DRAP1; TBP; FHL2; EDF1; BRCA1; BMI1; TFDP1; PARP1; PTTG1; HDAC2; RBM14; RUVBL2; CBFB; PA2G4; ITGB3BP; ENO1; DNAJC2; HNRNPD; EED; CENPF; PURA; HMGB1; CDK2; UBE2I; RAN; TFAM; HLTF; WHSC1; CHAF1B; HMGA1; SMARCA5; HOXA5; FOXM1; NPM1; SMARCE1; SSRP1; SFPQ; SMAD3; PSMC3IP; HOXC6; BLM; TRIM28; KLF6; ILF2; ECD; STAT5B; BATF3; ATF1; SNW1; NFKB1; CCDC59; ING2; EGR3; BAZ1B; DEK; IRX5; MAGED1; YWHAB; CTR9; HOXC10; BHLHE40; XBP1; BRD8; CEBPZ; ALX1; FOXD1; CCNC; NRIP1; CBX5; SAP30; ZBTB38; DNAJC1; HOXB7; NR2F2; SMARCA2; WWTR1; KLF2; MYB; HMGB3; ELK3; PSIP1; NR2F6; SATB2; SUV39H1; PITX1; HSBP1; DNMT3B; EGR2