Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16347	Azd-8330	GSE70138	MCF10A	Human	24h	0.12uM	EID0006

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	TSC22D3; TRIM22; CALCOCO1; FOXO3; ZMYM2; HBP1; IRF9; ELF3; NR2C1; TRIM33; JUP; NR3C1; FOXO4; NFIL3; HDAC5; BPTF; PDLIM1; CREBL2; NR5A1; NCOA2; ZMIZ1; NFKBIA; SOX4; ATF3; SREBF2; NCOA3; TRIM29; ZNF415; ZKSCAN1; ZNF331; FOSL2; CRYM; DDX17; NFE2L2; ZNF83; ZSCAN31; SIAH2; ZNF350; RCOR3; MXI1; MEIS1; FOXJ1; TGIF1; BCL6; ERBB2; ZNF426; ING4; IRF6; ZNF467; PNRC1; ZNF44; STAT6; LPIN2; PAWR; TRIM16; CHD3; KLF5; REL; ID2; WNT4; ARID4B; ELF1; ZNF33B; ZNF665; ZNF140; BTG1; ZBTB1; CITED2; PEG3; SP110; KAT2B; TCF12; PHF20; IRF7; BASP1; RLF; ZBTB16; BAZ2B; EHF; ARID5B; FOXO1; RREB1; ZNF91; CUX1; RSF1; MED13; MAF; ZNF43; MYT1L; ZNF165; ZNF160; HTATIP2; TOB1; ZNF532; STAT1; OSR2; TP63; VGLL4; ASCL1; SMARCD3; TOX; VDR; HLF; INSM1; KDM5B; MYCN; ZNF652; RORA; TRIM24; HMGN3; MYRF; SNAI2; PLAGL1; AHR; ID3; ADRB2; ZIC1; KDM5D; GATA6; TOX3; CREG1
Down-regulation	94	FOSL1; HMGA2; CDK2; MYBL2; CCNA2; EGR1; EZH2; FOXM1; HMGB2; TFDP1; DNMT1; BRCA1; SSRP1; PSMC3; RUVBL1; TLE1; CHAF1B; PTTG1; CENPF; TAF1A; PSMC3IP; RBL1; PA2G4; SATB2; DRAP1; WDHD1; WHSC1; ETV1; RAD21; RUVBL2; GMNN; PARP1; NRF1; HMGA1; CAPN15; HNRNPD; NELFB; NOC2L; BLM; YEATS4; TAF5; ELK1; E2F1; TFAM; PPRC1; TRIM28; AATF; HMGB1; NUP62; ENO1; CBFB; MTF2; ETV4; BCLAF1; CALR; C1QBP; EDF1; CCNE1; CBX6; SUB1; UBE2I; RBM14; EGR3; ING3; NPM1; BATF3; DEK; ATF5; ZFHX4; TRIP6; PURA; RBBP8; AGO2; SLC2A4RG; BMI1; PTRF; ETV5; YWHAB; SUV39H1; DLX2; HOXB7; PSIP1; MYBL1; ZEB1; FOXG1; EGR2; WWTR1; ZBTB18; ELK3; SOX9; PBX3; LEF1; PPARG; ID4