Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16346 Azd-8330 GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 222 CALCOCO1; IRF6; FOXO3; ELF3; ATF3; HBP1; PBXIP1; JUP; CREBL2; MNT; TSC22D3; IRF9; ZNF117; PNRC1; ZNF224; MEIS2; CSDC2; ZNF426; PRDM2; TRIM22; TRIM29; MZF1; HOXB3; FOSL2; ZKSCAN4; ZNF768; BCL6; DYRK1B; SALL2; ZNF195; AES; ZFPM2; ZSCAN31; ZBTB48; CDIP1; ZNF444; ZNF358; BTG1; ARID5A; NFKBIA; ZNF264; TRAK1; L3MBTL1; ID2; ZMIZ1; NFKB2; SIM1; ZNF423; ZNF362; WNT4; ZNF219; HIF3A; ZBTB3; GON4L; TSHZ2; FOXO4; FOXN3; YEATS2; ZKSCAN1; ARHGAP35; HINFP; ZNF33B; RFX5; HSF4; ZNF669; THRA; JUN; ZNF165; MXI1; SPI1; NR2C1; PAX8; PEX14; MYF5; AFF2; RBL2; ZNF85; ING4; GLI2; CUX1; PAWR; ZNF268; NCOA2; SUPT7L; ZBTB44; ZNF112; HDAC5; MYCL; INSM1; BCL3; MED25; ZNF91; SRCAP; RERE; HESX1; PRDM12; EHF; MNDA; EMX2; ZNF345; SIN3B; ERBB2; SOX2; EPAS1; NFAT5; TCF7L1; SP110; ZNF43; ZBTB20; IRF3; REL; IRF1; ZNF136; STAT6; ZNF611; KLF13; MEIS1; ZNF44; ID4; PDLIM1; CERS4; BNC2; NHLH2; ZNF529; ZNF544; MEOX2; MEF2C; OSR2; SOX4; ZNF334; ZNF140; TRIM16; ZNF467; SNAI2; BACH2; ZNF665; ZNF536; HMBOX1; IRF7; TEAD3; CEBPD; BAZ2B; SMARCC2; GTF2I; ERBB4; NFATC4; TP63; PPARGC1A; ZNF160; RORA; INSR; ZNF93; LDB1; DDIT3; KDM5A; SOX17; GRHL2; ZSCAN18; ISL1; ZNF606; JUND; ASCL1; HDAC9; TCF4; TCF15; HEY1; TLE1; ZNF652; ZHX2; GATA6; CRYM; WWC1; MEOX1; TXNIP; SIX2; REPIN1; TCF7L2; NEUROD1; SOX3; YAP1; ZNF331; RSF1; ZNF430; KLF7; HTATIP2; SATB1; ARID1A; ZIC3; MAFB; MECOM; EBF2; ZNF232; BCL11A; FOSB; ZBTB16; ARNT2; SMAD6; EYA1; SIX3; TWIST1; ZIC1; CBFA2T3; HAND1; CUX2; ID1; MYCN; CTBP2; ZNF721; ID3; MYRF; HOXB2; HMGN3; HOXB6; VGLL4; SPDEF; PBX1; SMARCA1; TRIB3; DACH1; CREG1; TBX3; E2F2
Down-regulation 88 FOSL1; HMGA2; EZH2; CCNA2; EGR1; SUB1; ITGB3BP; HMGB2; RHOA; BRCA1; FOXM1; BMI1; BCLAF1; CENPF; PTTG1; CDK2; DRAP1; TFDP1; MYBL2; PSMC3; GMNN; NUP62; MYCBP; TCERG1; RUVBL1; CHAF1B; ASH2L; TBP; WHSC1; HDAC2; HSF2; ILF2; SSRP1; PSMC3IP; SATB2; HNRNPD; DEK; WDHD1; DNAJC2; RUVBL2; CBFB; ING2; BLM; HMGB1; TAF5; CCNE1; RNF138; XRCC6; PURA; RBM14; CBX3; PA2G4; RAN; HLTF; EDF1; CCDC59; TRIM28; SMARCE1; EGR3; RNF4; ING3; STAT3; CRY1; YWHAB; ZNF281; CEBPZ; ETV4; MYBL1; NKX2-2; TBL1XR1; PMS1; CALR; C1QBP; NPM1; IKBKAP; BATF3; JARID2; HOXC10; TGFB1; SUV39H1; SAP30; ENO1; PSIP1; PITX1; MNAT1; ELK3; CREB1; MSX1