Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16344 Azd-8330 GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 171 ELF3; CALCOCO1; TSC22D3; PBXIP1; FOXO3; RFX5; CREBL2; ATF3; JUP; PNRC1; IRF9; HDAC5; YEATS2; FOXO4; IRF6; PRDM2; CSDC2; FOSL2; TRAK1; ZNF768; ZBTB16; MNT; MKL1; MEIS1; NFKBIA; BTG1; TRIM22; ING4; SRCAP; RARG; TRIM16; ZMIZ1; ZNF117; TEAD3; HBP1; TRIM29; ZNF415; ID2; BCL6; SP100; SALL2; SIAH2; ZNF467; HOXB3; L3MBTL1; OVOL2; REL; THRA; ZSCAN31; ZKSCAN1; CDIP1; TSHZ2; MXI1; ZNF224; ARID5A; PDLIM1; ZNF573; PBX1; ZNF688; INSR; EHF; ZNF665; MEIS2; IRF7; ZNF44; CBX7; SOX17; NFKB2; GRHL2; RING1; ZNF133; WNT4; FOXK2; MYCL; ZNF195; OSR2; JUND; ZNF264; ZFHX3; SSBP2; ZNF91; NFE2L1; TP63; ZNF160; JUN; ZNF112; AR; SOX4; ZNF536; RNF10; SNAI2; ZNF165; CUX1; TLE1; ZNF611; ZNF136; HMBOX1; ERBB2; ZNF33B; KLF5; RBL2; FOXC1; SP110; ESR1; BCL3; KLF9; PAWR; KLF4; CERS6; HOXB2; TCF15; ZNF268; ZNF623; ISL1; FOXN3; KDM5A; SREBF1; NFATC4; TXNIP; ZNF331; ZNF587; EP300; HOXB6; HEY2; CERS4; EYA2; CRYM; ID1; HDAC9; TCF7L1; ELF1; NCOR2; FOSB; ARID5B; PLAGL1; RSF1; KLF7; BCL11A; MAF; ID4; ZNF652; GATA6; HMGN3; HEY1; TCF4; MEOX1; MYCN; MYRF; MNDA; ZNF721; TRPS1; SALL1; BRD4; MITF; ARNT2; VGLL4; EMX2; SMAD6; RORA; TFEC; MECOM; ZNF423; TBX3; TOB1; TWIST1; AHR; CREG1; TOX3; KLF10; PEG3; ADRB2
Down-regulation 100 FOSL1; HMGA2; EZH2; CCNA2; MYBL2; CDK2; ETV1; BRCA1; FOXM1; HMGB2; TCERG1; PTTG1; DRAP1; WHSC1; CHAF1B; CENPF; WDHD1; TFDP1; DNMT1; HSF2; CBX3; SSRP1; ILF2; PARP1; TAF1A; BCLAF1; PSMC3; PSMC3IP; RAN; YEATS4; DNAJC2; RBL1; NUP62; GMNN; TAF5; PA2G4; DEK; FOXD1; HMGB1; MTF2; BLM; TEAD4; BMI1; ITGB3BP; ETV4; BAZ1B; SUB1; RUVBL2; CBFB; HNRNPD; RBM14; ING2; TRIM28; SATB2; ING3; ARNTL2; TFAM; BATF3; BRIP1; CCNE1; NPM1; MYBL1; WWTR1; NFKB1; CCDC59; AGO2; PAXBP1; CRY1; HLTF; EGR4; MED1; HMGA1; SAP30; E2F8; SIM2; SUV39H1; ENO1; NFE2L3; MYB; RUNX3; CEBPZ; EGR3; CITED2; MAGED1; ZEB1; DLX2; NKX3-1; ZBTB18; BAZ1A; YWHAB; HMGB3; ELK3; PPARG; TBL1X; BASP1; ETV5; KDM5D; PBX3; EGR2; SATB1