Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16336 Cgp-60474 GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 667 EGR1; ZFPM2; ERBB4; HOXB1; ZNF117; PRDM2; NEUROG1; ZNF91; BRWD1; ZNF415; THRB; HOXD3; ZSCAN18; KLF13; NFATC3; CRX; ZNF331; ATF3; NFIX; ST18; ZNF667; SALL2; NR4A2; MEF2C; PRDM14; HAND2; ZNF671; GBX1; ZBTB44; ZNF154; ZNF264; CEBPE; CALCOCO1; PDX1; LIN28A; PBXIP1; ZNF250; TBX21; NEUROD6; RFX1; NR5A2; ZNF500; FEZF2; ZNF536; ZNF682; ZNF85; WHSC1L1; HOXB5; CHD2; PAX1; EMX1; ZNF484; TCF4; GLI2; ZNF711; CDIP1; ZNF350; MAML3; NR5A1; PRDM1; IRF9; ZNF177; ZNF816; NPAS1; WT1; RARG; TSHZ2; PRDM12; SCRT1; ZNF506; PHF1; HIC2; CBX7; ZBTB3; ZNF362; ZNF665; LHX3; FOXH1; MEIS2; NEUROD2; CAMTA2; PRDM8; ZNF257; ZNF221; PCGF3; ALX3; LZTR1; ZNF358; NR1I3; ZNF345; ZNF93; RORB; PAX7; ZNF549; VENTX; SPI1; ZNF75D; NFATC4; ZNF141; SOX17; ZNF136; FOXN1; NEUROG3; TAF1C; ZBTB7B; ZKSCAN3; PROP1; ZBED2; AIRE; TULP1; SIX6; HEYL; CBX2; SOX21; TLX2; SKI; HOXD12; ZNF654; ZSCAN2; NOCT; MAPK8IP1; CARF; ZNF224; CDX4; SRY; ESR2; KAT2B; POU3F3; ALX4; ZNF223; ZNF467; FOXB1; ZNF556; HOXC8; SOX2; ASCL3; OVOL1; ZNF669; MED12; ZNF814; AFF2; ZNF701; AFF3; HIF3A; NRL; TAF1; TP73; ZNF606; ESR1; RAX; ONECUT1; ZNF76; PRDM9; ZNF471; ZNF695; POU6F2; ZNF43; ZNF253; HOXA3; DLX5; ZNF132; THRA; BARX1; BPTF; ZNF768; HDAC5; ZNF778; RING1; TEF; ZNF219; TAF6L; ZNF274; DCC; TFDP2; ZSCAN9; ZFP2; NEUROG2; MAFK; NR4A1; GRIP1; ZNF79; SNAI1; HSF4; HOXB8; SOX3; SSX7; ZNF124; TLX1; SOX1; ZNF343; FOXN3; SOX18; KLF15; NKX2-5; DYRK1B; RFX2; ZNF460; TBR1; ZNF440; NEUROD4; RXRG; ETV3; NFKB2; GLI1; DLX2; POU4F3; RORC; PAX2; ZNF208; GFI1B; ZNF195; ZNF423; BRDT; IKZF4; POU3F4; BCL11A; ZNF550; DOT1L; ZNF688; CIITA; ZNF426; MED31; LHX5; RFX3; ZNF239; TONSL; UTF1; EVX1; ETV2; TCEA2; FOXL1; NR6A1; NR4A3; ZNF254; ZNF268; GBX2; EP300; FOXE3; ZNF135; ZNF140; NHLH2; ZNF749; TBX6; ZKSCAN4; RBPJL; ARID5A; ZBTB17; CREBL2; ONECUT2; OVOL2; NKX6-1; FOXD3; ZNF81; ZNF835; ZNF44; ZIC3; IKZF2; VGLL1; MLLT1; ZNF74; ZNF589; SCAI; ZIC4; NR0B2; ESRRB; HIC1; GSC2; EMX2; HMGA2; SSX3; ATOH1; PRDM16; ZNF780B; ARL2BP; MXD3; NANOG; MZF1; MXI1; SOX5; LHX2; ZNF273; ZNF329; SP4; ZNF391; PAX3; ID3; HESX1; LMX1B; CRTC1; HOXA4; TULP2; ZNF573; TFAP4; TFAP2A; HEY1; TWIST1; ING4; VSX1; AR; PITX3; ZNF770; HIPK2; ZNF562; ARRB1; ZNF80; L3MBTL1; MYCN; ZNF544; ZNF234; ZNF211; FOXJ1; TUB; ZNF507; ZNF205; MECP2; HOXB13; SOX14; HMBOX1; TBX4; IFNB1; ID4; ZNF675; ZNF235; BNC1; TBX5; CUX2; ZNF174; GRHL2; ZNF155; CREM; BNC2; RBL2; E4F1; TBX10; FOXC2; HINFP; NKX3-2; ATF7; ZNF613; HNF1B; IKZF3; EHMT1; HES2; ZIM2; HBP1; ZNF214; KMT2D; KDM4C; GCM2; CERS4; HOXD13; ARID3B; SIX5; MSX2; VHL; ELF4; REL; HOXA6; ZBTB48; HOXB3; HOXD1; ZNF41; ZKSCAN8; ZNF225; PAX4; DLX6; ZFY; ARID5B; ZNF175; ZNF674; ZNF771; SRCAP; ACTL6B; EYA3; PRRX1; LBX1; SIM1; TAL1; WNT4; HAND1; ZNF571; HOXC5; STAT2; GATA1; PKNOX2; ZNF33B; STAT4; THAP9; ZFHX2; HOXD9; MDM2; POU1F1; ZNF442; ZBTB32; NHLH1; PPARD; HNF4G; ZNF10; MEIS1; EZH1; TCFL5; IRF6; NFAT5; NCOA2; ZNF334; DLX4; HOXB6; ZNF407; ZNF14; ZNF623; POU2F2; MYF5; ZNF493; MYEF2; ZXDB; KLF8; SPDEF; HNF4A; NFIC; MKL1; ZNF611; ZNF222; HDAC9; ZNF287; PRRX2; ZNF184; RORA; ZNF133; ZFP69B; NR2E1; TBX19; POU5F1B; ZNF32; HLX; TDP2; PHOX2A; BHLHE41; SUPT7L; ATF6B; ZNF157; GCM1; MYT1; VPS72; ZEB1; POU2F3; MED25; E2F4; SUPT3H; SHOX; ATN1; HHEX; MEOX1; HEY2; POU6F1; POU3F2; PAX6; ZSCAN16; ZNF180; ZNF34; MDM4; NACA2; ZNF430; EHMT2; MYBL1; PEG3; KDM5C; TGIF2; FOXP3; NCOA3; SIX3; ARHGAP35; TCF21; NKX2-8; NEUROD1; FOXI1; MYRF; KLF11; PRDM10; MBD4; KLF7; PPARA; LMCD1; GLI3; CBX4; EN2; AEBP1; AES; HOXA2; ZNF419; TAF4B; THAP7; VAX2; SKIL; ZNF304; TGFB1; ZBTB43; DMRT1; ZNF492; TERF1; SOX10; HIRA; ZKSCAN1; ZNF529; EPAS1; E2F1; NAB2; ZNF480; NLK; TLX3; BACH2; IRF7; RSF1; MAK; PBX1; E2F2; ZXDC; CCNH; MAF; SSBP3; ZNF551; ZBTB7C; TRPS1; TCF15; BHLHE40; ETS1; CD3D; PRDM5; ZSCAN31; GATA6; FOSB; ZKSCAN7; HOXD11; TBL1Y; SUPT6H; FLI1; SMAD6; TFDP3; SP140; HMX1; PBX2; TAF7L; LHX6; PEX14; ZNF528; APBB1; TULP3; TOX; NR1I2; TTF2; NKX2-2; NFE2; CDX1; LYL1; POU4F2; HOXB2; MYCL; ASCL2; FOXO4; FOXF2; MXD4; TBX1; ZNF248; SMARCA1; EN1; HIVEP1; PHOX2B; FHL5; CITED1; FOS; FOXF1; ZNF532; EGR3; PRMT2; ZNF552; NR2F1; CREB3L2; EBF2; ZNF512B; ARID3A; CBFA2T3; BCL3; KLF3; ZNF587; TFEC; FOXG1; INSM1; HLF; TLE2; JUP; ARNT2; TRIM24; ZNF652; PDLIM1; INSR; CALR; SMARCC2; NFATC1; KLF9; TCF7L2; GFI1; ZFHX4; TFAP2B; MAFF; DBP; ZNF107; ZNF148; FUBP1; MEOX2; SALL1; MSX1; TCF7L1; FOXL2; NR1H4; OLIG2; ZNF131; SOHLH2; MECOM; KAT6B; MED14; ZNF394; NR1H2; ZNF165; SHOX2; FOXE1; TLE4; CDX2; ZMYND8; PNRC1; ZNF232; BBX; JUN; SSX1; GATA2; SOX11; CUX1; ESRRG; OSR2; TRIB3; SMAD7; DAXX; SNAI2; CREB1; PSIP1; PITX2; SPIB; TBX3; DACH1; LOXL2; SP140L; EGR2; CHD9; SATB1; TCF7; DMTF1; NFE2L3; TRIM22; POU2AF1; ZNF586; IKZF1; LITAF; TXNIP; FOXA2; HMGN3; ZEB2; LEF1; SSBP2; TBX2
Down-regulation 202 PUF60; USP22; FHL2; TCERG1; MYC; EZH2; NUP62; FOXJ3; TP53; HDAC2; CCNA2; TBP; HSF2; SFPQ; ATF1; KAT5; RBM14; UBE2I; SSRP1; AATF; CDK7; SNW1; RUVBL2; ATF6; TRIM28; MED6; CRK; ZNF146; NKX3-1; BCLAF1; DNAJC2; ITGB3BP; RB1; NCOA6; DEK; BAZ1B; RAN; ZNF473; PTTG1; MED1; REXO4; PMF1; HNRNPD; KAT7; TAF5; TBPL1; TLE1; CEBPG; TRIM16; TRIM32; GTF2A2; NELFB; ELF1; CTR9; CENPF; PATZ1; RBBP4; NR2F2; MBD2; MED23; SMARCC1; BRCA1; XRCC6; SMARCE1; ADNP; HMGB2; HMGA1; ATF4; FOXM1; UBP1; RNF138; PLAGL2; RNF6; ZNF410; HOXC6; ZBTB11; SAP30; PA2G4; ZBTB24; BRD8; CNOT6; NRIP1; FOSL1; EED; MTA1; PPRC1; TCF12; HOXA10; ECD; SF1; CNOT1; TBL1XR1; NPM1; RRN3; MLX; BRD3; XBP1; NFYA; CRY1; YBX3; BRPF1; GTF2IRD1; PHF2; SP3; CBX3; HOXA5; ING2; TRIP6; ORC2; DDIT3; SFMBT1; SNIP1; HDGF; ERCC3; RBM39; FOXO3; CCDC59; TTF1; MED24; BAZ1A; NFYC; ZNF263; CDC5L; YAF2; PSMC3IP; RNF4; SMARCA5; TMF1; SIAH2; TCF20; PHF20; USP21; RNF111; HOXC10; TRIM27; ZBTB18; GATAD2A; BMI1; KDM2A; NONO; PRKDC; SETD2; SMARCD2; RBBP7; CHD1; ILF2; LIMD1; NAB1; TSC22D1; DR1; SREBF1; HMGB1; RREB1; MED4; CBFB; SOX4; MAX; CEBPB; JARID2; CBX5; MTDH; ADRB2; HMGB3; CEBPZ; KAT6A; TBL1X; NFIB; SMAD3; HDAC1; C1QBP; MED21; ARID4B; NCOR1; CTBP2; KLF5; NCOA4; BLM; SCAND1; TEAD4; SOX9; ABL1; YBX1; ENO1; CDK8; AFF1; PIR; PURA; COPS2; HOXB7; CHD7; YWHAB; MAGED1; AGO2; ETS2; IRX5; REPIN1; TRIM29; TSC22D3; PITX1; SUV39H1; BRD2; BASP1