Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16335 Cgp-60474 GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 713 ERBB4; EGR1; BRWD1; HOXB1; ZKSCAN4; ZNF331; ZNF117; ZNF415; ZBTB44; IRF9; MEF2C; KLF13; THRB; PRDM2; CDIP1; ZNF350; GLI2; HDAC5; NFATC3; ZNF671; EMX1; CALCOCO1; HBP1; NEUROG1; HIF3A; ZNF91; ZSCAN18; HOXD3; PRDM12; ZNF154; ZNF85; ZFPM2; ZBTB3; PAX1; LHX2; TBX21; GBX1; NR0B2; ZNF79; ZNF345; ZNF682; VENTX; FOXH1; CIR1; ZNF223; NEUROD2; SIX6; NFIX; ZNF136; ZNF701; PRDM14; AFF2; ZNF500; ZNF573; CHD2; SOX21; OVOL1; NEUROD6; CRX; SNAPC4; SCRT1; RARG; SALL2; ZNF235; ONECUT1; RBPJL; THRA; ZNF75D; NOCT; ZNF221; SOX18; ZNF222; CSDC2; ZNF536; CEBPE; TAF1C; NR5A2; TFDP2; WT1; DYRK1B; CREBL2; ID4; ASCL3; ZNF93; LHX3; ZNF654; MAPK8IP1; DLX2; ST18; NR5A1; PHF1; RAX; TULP1; ZNF816; SRY; BNC2; NR1I3; ZKSCAN3; ZNF140; RFX1; PROP1; HMBOX1; ZNF423; ZNF175; ZNF264; ZNF506; PAX7; ZNF667; FEZF2; SPI1; SOX2; CUX2; NAB2; RORC; PAWR; ZNF253; CBX7; ZNF778; ZNF665; NRL; ZNF141; PAX2; HEYL; MED12; ZNF205; PRRX1; ZNF329; NFATC4; TP73; CDX4; ALX4; BARX1; ZFP2; LIN28A; ZNF257; MEIS2; HMGXB3; NEUROG3; ZIM2; ZNF174; ZNF195; HAND2; ING4; TLX1; MAML3; MED25; EVX1; NKX2-5; ZNF669; ZNF304; FOXN1; NHLH1; RORB; PDX1; ATOH1; SSX7; E4F1; NPAS1; IKZF2; ATF3; GRHL2; ZSCAN2; MZF1; ETV3; ZNF132; ZSCAN9; ZNF549; PAX6; NHLH2; TBR1; NR6A1; HOXC5; MAP3K10; FOXE3; HDAC9; HNF1B; MXI1; ZNF770; ZNF343; POU6F2; PITX3; MYCN; HOXD9; ZNF444; ZNF219; ZNF467; ZNF8; ZSCAN16; TBX4; SOX17; AIRE; ZNF250; MBD4; GBX2; ZNF695; HSF4; TULP2; POU3F3; ZSCAN32; CBX2; MXD3; ZNF507; SCAI; ZNF43; ZNF440; ZNF606; ZNF711; PRDM16; TLX2; IKZF4; TEF; PRDM9; ZNF362; NEUROD4; ZNF239; POU3F4; ZNF268; NKX3-2; ZNF471; ETV2; ZIC3; FOXB1; ZNF550; ALX3; FOXL1; HOXA6; NEUROG2; ZNF112; SNAI1; ZBTB17; TCEA2; PNRC1; ZNF224; HINFP; ZNF10; TONSL; CRTC1; HESX1; DCC; TLX3; PRDM1; ZNF814; PPARD; PBXIP1; MAK; KLF15; YBX2; HIPK2; POU4F3; HOXB8; PKNOX2; IRF6; ZNF177; HOXB5; ZBTB7B; LMX1B; MYCL; SUPT7L; GRIP1; RFX3; ZNF142; DOT1L; TSHZ2; FOXD3; BACH2; LMCD1; PRDM8; HNF4A; TCF21; SOX3; ZNF484; AR; INSM1; TAF6L; MYRF; BCL11A; BNC1; ZNF771; MED31; ZNF225; ZNF254; LZTR1; CCNH; ACTL6B; ZNF34; HIC1; VGLL1; STAT2; HOXD12; ZFP30; ZNF180; IRF5; WHSC1L1; PRDM10; ESR2; FOXI1; CBX4; RING1; CRYM; ZIC4; ZNF529; CIITA; TP53; ZNF76; ZNF426; TBX5; SIX5; POU2F2; NANOG; EZH1; NKX6-1; STAT4; SOX1; POU6F1; CBL; HOXC8; NKRF; ZNF214; ZXDC; ESRRB; SOX14; NFKB2; NR2C2; SSBP3; PAX3; ZNF835; SOHLH2; ZFHX2; NCOA3; PPARA; BRDT; TBX6; CUX1; ZNF688; ZNF623; HOXA3; ZNF215; VAX2; VSX1; EMX2; ZNF208; ZNF571; HMX1; SP4; FOXJ1; TUB; L3MBTL1; ZNF556; ZNF234; HLX; HNF1A; ZNF155; ASH1L; GSC2; WNT4; HNF4G; POU3F2; TWIST1; CAMTA2; TFDP3; TGFB1; GCM1; ZNF33B; TCF4; CREM; ZNF675; ZNF211; NEUROD1; SKIL; RBL2; MLLT1; ONECUT2; ZFP37; FUBP1; ZNF749; KLF7; TBX10; ZNF334; LHX5; ATF6B; FOXF2; HOXD13; SOX5; ZNF81; SIX3; ZNF200; ZNF589; RFX2; CCNT1; ZNF780B; LHX6; LMO1; MECP2; NR2C1; DLX4; ZNF532; CBFA2T3; E2F1; EYA3; LBX1; OVOL2; THAP9; ZXDB; EHMT2; HES2; HOXC11; KLF11; PRMT2; SKI; DACH1; ZNF274; SHOX; ZNF768; PIAS1; ZNF562; ZNF391; ZNF80; SRCAP; ARID5B; IFNB1; MYF5; ZNF442; GATA6; ARRB1; PCGF3; UTF1; ZNF41; EP300; INSR; DLX5; E2F4; ARID3B; PEG3; FOXN3; PRDM5; TEAD3; POU2F3; LHX1; CREBZF; KLF3; ARID5A; SPDEF; FOXP3; ZNF35; NKX2-8; PAX4; IKZF3; SMARCA1; ZNF287; ARL2BP; ZNF407; ZNF135; GCM2; TFAP2A; ZNF557; NR4A3; TCF7L2; ZKSCAN8; VHL; AFF3; POU5F1B; CBFA2T2; MKL1; NCOA2; PLAG1; SUPT5H; SMAD6; CARHSP1; REL; HOXA4; ZNF613; CARF; GATA1; ESR1; SUPT3H; CDX1; ZNF394; ZNF273; KLF8; KMT2D; ZNF74; ZNF611; HAND1; ZNF493; ZNF674; HOXD1; NR4A1; EHMT1; ZNF492; THAP10; ZNF552; NR2E1; HOXC4; YEATS2; ATF7; RARB; ASCL2; SSX3; SIM1; APBB1; NR4A2; KDM5C; ESRRG; ZNF544; POU1F1; ZKSCAN1; ZNF432; LYL1; MYOD1; SUMO1; FOXC2; HDAC6; KAT2B; PBX1; HOXA2; ZNF157; ZNF710; TAF7L; AEBP1; TBX1; RXRG; TFEB; ZBTB20; EN2; ZNF232; ZNF419; PRDM13; SOX11; TOX; TBL1Y; FOXF1; MYEF2; ZNF3; BAZ2A; VPS72; DLX6; ETS1; ZNF480; ZMIZ1; GLI1; TBX19; TTF2; MEIS1; BACH1; CD3D; HDAC11; HEY1; ZSCAN31; PBX3; MNX1; JUP; PRRX2; NFE2L3; NR1H4; NR1H2; LDB1; HHEX; PEX14; TDP2; NR1I2; ZKSCAN7; RSF1; ZEB1; ZNF184; ZNF44; GATA4; MEOX2; DBP; ELK4; MXD4; ZNF124; MSX2; GFI1; BPTF; CERS4; MED14; ZNF354A; NFIC; MECOM; SALL1; CAMTA1; BARX2; SAP130; HOXB13; HIC2; EPAS1; ZNF133; GFI1B; POU4F2; ZNF134; NFE2L2; CEBPD; OLIG2; ZFY; ZBTB7C; NACA2; ZNF510; BHLHE41; ZNF165; ZNF248; GLI3; MYT1; MYBL1; E2F8; ZNF528; ZFP69B; GTF2A1; ZNF324; ZMYND8; PROX1; TDRD3; TRIB3; ZNF12; TCF3; MEOX1; TRPS1; SP140L; FOS; MYT1L; NFAT5; PIAS4; TFAP2B; ZNF587; MLXIPL; CDX2; TULP3; FOXG1; ZHX2; PHIP; PHOX2A; SUPT4H1; SMARCC2; TXNIP; PAX5; IRF1; BAZ2B; ID3; ING3; YAP1; ZNF430; GATA2; FOXL2; PITX2; MDM4; DMTF1; HIRA; LZTS1; ZNF217; TGIF2; ZNF551; CREB1; SOX13; CCNE1; KLF9; FOXE1; EYA1; NKX2-2; ZBTB43; KAT2A; IRF7; ARID3A; SHOX2; NR2F1; TLE2; MXD1; TOX3; NR1D2; ZNF107; TCF7L1; SLC2A4RG; IKZF1; TFEC; DAXX; PHOX2B; NFE2; SSBP2; IRF8; ZBED2; ZNF586; STAT1; TRIM24; OSR2; ARNT2; FOXA2; ZNF160; FLI1; KAT6B; TCF7; HEY2; VDR; RORA; ZNF131; CITED2; PGR; SATB1; HLF; TBX3; TRIM22; SMAD7; ZNF652; ISL1; PLAGL1; MAF; TBX2; LITAF; NR2F6; EGR2; E2F2; ZIC1; MYB; LEF1; SSX1; PPARG
Down-regulation 191 PUF60; USP22; MYC; FHL2; CRK; NUP62; FOSL1; TCERG1; EZH2; NFKBIA; TBP; ATF1; HDAC2; ZNF146; SSRP1; ATF6; SNW1; RUVBL2; RBM14; GTF2A2; CCNA2; ZBED4; ATF4; TRIM28; SMARCE1; PTTG1; RBBP4; ZNF672; SFPQ; UBE2I; ILF2; PRKDC; HNRNPD; BMI1; MED1; MED24; MED6; BAZ1A; ELK3; MAGED1; MTDH; XRCC6; XBP1; ITGB3BP; YBX3; PMF1; CTR9; TRIM16; CENPB; RAN; RFX5; CBFB; SMARCA2; NONO; NFKB1; AATF; SREBF1; ZBTB24; SCAND1; KDM2A; RNF6; CDK7; TFDP1; SMAD2; BAZ1B; HOXA10; SAP30; BRD8; PATZ1; RNF4; HOXC6; HMGB2; EED; MBD2; PPRC1; NR2F2; SMARCC1; PARP1; SMARCA5; DDX5; TLE1; HDAC1; JARID2; GATAD2A; SUB1; CRY1; NPM1; APEX1; HSF2; PIAS2; RCOR1; PHF2; YBX1; DR1; UBP1; DNAJC2; TAF10; ARID4B; SF1; NFIL3; CENPF; BCLAF1; WHSC1; RNF138; NCOA4; MAX; NCOA6; ASH2L; HOXB7; FOXO3; PIAS3; CEBPB; PCGF2; NKX3-1; TCF20; FLNA; CNOT1; HOXA5; MLX; CEBPG; HMGB1; RBBP7; CCDC59; SMARCD2; ADNP2; KLF5; POLR2A; MEF2A; ENO1; NFYA; ZBTB11; TRIP6; KAT7; HMGB3; BHLHE40; GABPB1; COPS5; RUNX1; TRIM32; TBPL1; ELF1; DEK; AGO2; TBL1X; NPAT; ECD; FOXK2; PA2G4; PIR; NEDD8; NCOR2; SOX9; PQBP1; HDGF; HOXC10; TCF12; ADRB2; ZNF593; C1QBP; ZNF410; HMGA1; NAB1; RNF111; ZBTB18; PBRM1; VEZF1; ERBB2; BCL10; NRIP1; AFF1; PURA; BASP1; TBL1XR1; CEBPZ; TRIM29; HLTF; CDK8; PITX1; PHF20; FOXC1; ETS2; AHR; NFIB; NRBF2; KDM5B; IKBKAP; GTF3A; KLF4; ZFP36L1; KDM5D; SUV39H1