Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16330 Pf-431396 GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 194 BRWD1; SCRT1; E2F2; ZNF141; CHD2; NFATC3; SIX6; ZBTB3; SOX3; BNC1; SNAPC4; VENTX; ZNF217; ZNF549; POU4F3; FEZF2; HOXD12; ZNF682; SOX18; ZNF675; ZNF117; NEUROG2; HOXB5; TLX2; ZNF254; TEF; SALL2; ZNF257; ZNF749; GSC2; ZNF214; FOXD3; ZNF81; ZNF154; POU6F2; ZNF695; THRB; AFF2; POU3F3; IRF9; DOT1L; ZNF234; NANOG; ZNF780B; ZNF674; KLF13; SOX14; ZNF80; ZNF500; SRY; THAP9; BARX1; FOXE3; PRDM9; ZNF334; PAX4; UTF1; HESX1; POU2F3; PAX9; GCM2; ZNF350; FOXB1; TLX3; VHL; POU1F1; GBX2; CDIP1; NR1H4; TP73; PRDM12; HOXB8; ZNF407; KLF8; RFX3; ZNF132; NR5A2; ZNF467; ZNF12; SOX21; PRDM10; SOX1; ZNF345; ZNF770; ASCL2; HIC1; MEIS2; ZNF440; ZNF155; MYBL1; IKZF3; ZNF268; ZNF157; SIM1; GFI1B; SCAI; BRIP1; ZNF273; CIITA; BRCA2; ZFP69B; CUX2; LIN28A; HDAC9; ZNF136; ZNF10; DMRT1; SKIL; KLF11; GLI2; ZNF225; ZNF492; TCEA2; BACH1; ZNF124; SOX2; ZIC3; ARNT2; BACH2; ZNF711; HOXB6; SIX3; ZNF331; TFAP2C; PEX14; ZNF33B; FOXF2; HIC2; FOXN3; NFATC4; NEUROD1; TRIB3; JAK2; E2F8; WNT4; ZNF43; BNC2; TGIF2; NFE2; TCF7L2; ZNF165; EN1; PBX3; ERBB4; KLF7; SOX11; ZNF131; VGLL1; CRYM; TCF7L1; ZNF512B; ZNF91; CERS4; SHOX2; BRD4; BCL11A; PHIP; CBFA2T3; HOXD1; ZHX2; MEOX2; TULP3; SOX17; KAT2B; MXI1; NFE2L3; SMAD1; TBX1; DLX2; POU2AF1; PAX6; VPS72; ZFP36L2; TWIST1; SOX13; MEOX1; TP63; TGFB1I1; ZEB1; SMARCA1; HLF; PITX2; DLX5; ISL1; ZNF423; NR2F6; TFEC; OSR2; AEBP1; TXNIP; ZIC1; ID3; ADRB2; FOS
Down-regulation 30 TP53; EGR1; HLTF; BMI1; RAN; ZBTB38; BRD8; TRIM28; CHD7; FOXC1; JARID2; C1QBP; CTR9; HOXC6; SMARCA2; RBBP7; HMGB2; RBBP4; HOXC10; HSBP1; MAGED1; TRIM16; CEBPA; TRRAP; MNAT1; NR2F2; GTF3A; FOSB; PIR; SUV39H1