Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16324 Gsk-1059615 GSE70138 MCF10A Human 24h 0.12uM EID0006
Types Number Response transcription factors
Up-regulation 38 ZNF586; IKZF1; ZNF134; TFE3; KLF1; ZNF443; HOXD3; ZNF91; PQBP1; PRRX1; PURA; SMARCA2; RBL2; CREB3L1; BLM; NCOA4; OLIG2; SUV39H1; BATF; MAGED1; TRIM32; ZBTB38; RBBP7; SMAD7; MECP2; EGR3; SMARCD3; SOX9; HSBP1; BHLHE40; NCOA1; NPAS2; ZIC1; SMAD6; GATA6; TXNIP; ZEB2; FOS
Down-regulation 35 HMG20B; SHOX2; ST18; IRF7; ARID1A; YAP1; HHEX; SOX11; CHD8; CUX2; TCEA2; TGFB1I1; GRHL2; MEIS2; SREBF1; FOXD1; DLX2; HMGA1; TP63; HLX; ZFP36L1; INSM1; NKX2-1; AEBP1; TCF21; PIR; IRF8; BAZ1A; ISL1; VPS72; ID1; TOX3; TWIST1; KDM5D; SATB1