Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16322 Gsk-1059615 GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 193 MEF2C; CALCOCO1; TSC22D3; HBP1; PBXIP1; SOX4; HDAC6; FOXO3; FOXO4; PRDM2; PNRC1; CEBPD; FOXN3; HDAC5; BRWD1; BPTF; L3MBTL1; ZNF117; SALL2; HMG20B; ZNF358; ZNF83; SPI1; ZNF688; MNT; CREBL2; NR3C1; MZF1; BTG1; ZNF500; ZNF76; ZNF33B; ZNF362; ERBB4; SETDB1; NCOA3; IRF9; HOXB13; IRF7; ZNF224; STAT2; HIF3A; BAZ2B; ZBTB16; ZNF667; ZNF133; SP100; ZBTB3; SIX6; ZKSCAN4; ING4; CIR1; ZNF217; ZNF345; ZNF444; CSDC2; PPP1R13L; TCEA2; ZNF606; KAT8; NCOA2; ZNF264; KLF13; DDX17; HOXD1; INSR; ARID5B; YEATS2; ZNF354A; CITED2; ZNF665; SP110; APBB1; TLE4; CARF; GLI2; ELF4; ZNF623; CBX7; UBE2B; NFIL3; NFATC3; LZTR1; ZNF75D; CDIP1; EZH1; BACH1; ZNF175; TRIM22; ZNF112; ERBB2; ZNF135; ZNF587; ZNF415; TCF4; BCL6; MBD4; ZNF711; NONO; BAZ2A; MED12; FOXO1; TCF7L1; SMARCC2; TCF15; PEX14; JUP; ZNF141; ZNF334; ZNF34; MECP2; TXNIP; HDAC9; ZMYM2; HIVEP1; NFE2L1; PCGF3; ZFPM2; ARID1A; TAL1; HMBOX1; GATA6; IRF8; PAWR; LPIN2; TSG101; JUND; PKNOX2; SCAI; JAK2; KLF11; ZNF254; FLI1; SMAD3; ARNT2; MEOX2; GRHL2; PBX1; ZNF532; STAT6; TGFB1; ZKSCAN1; ZMYND8; WNT4; ATF3; TFEC; KLF7; ZNF611; RSF1; CERS4; TCF7L2; LIN28A; KAT2B; ZBTB20; ZNF12; SOX17; ST18; PDLIM1; LMCD1; NR4A2; IRF6; TRIB3; MAF; MXI1; NFATC4; NFE2; SMAD6; NFE2L3; ZNF512B; ZFP36L2; ZIC3; CUX2; MED13; BCL11A; ZNF160; PHF20; ZSCAN18; ZNF91; KDM5B; ID2; VPS72; ZFP36L1; MECOM; MAFB; DACH1; AEBP1; MEIS1; SSBP2; ZNF652; PEG3; FOS; POU2AF1; MEIS2
Down-regulation 70 FOSL1; MYCBP; GTF2A2; RUVBL1; DRAP1; PUF60; TFDP1; RUVBL2; EZH2; PCBD1; MYBL2; GABPB1; HDAC2; WDR77; EGR1; PPRC1; PARP1; SUB1; C1QBP; BCLAF1; DNMT1; CBFB; EGR3; EED; CRY1; HNRNPD; RAN; PA2G4; PSMC3IP; ABT1; SFPQ; RBM14; HMGA2; PIAS2; TBPL1; RNF4; TRIM32; HLTF; YWHAB; EDF1; DNAJC2; CEBPZ; RNF138; CHD7; GATAD2A; NPM1; BRCA1; STAT1; HMGB1; PURA; PITX1; TSC22D2; SATB2; RBBP7; BATF3; BAZ1A; ENO1; HES1; ECD; ZBTB18; IRX5; ADRB2; FOXF1; LEF1; PIR; HOXC10; MNAT1; WWTR1; SUV39H1; BASP1