Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16321 Gsk-1059615 GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 383 HBP1; PAX8; CALCOCO1; PRDM2; TSC22D3; ZNF117; NR3C1; IRF9; FOXN3; ERBB4; FOXO4; CBFA2T2; ZNF85; CITED2; ZNF83; PNRC1; ZKSCAN4; SETDB1; ZNF354A; CREBL2; ZNF175; BTG1; HDAC6; ZNF250; CIR1; BRWD1; PBXIP1; SPI1; SOX4; SALL2; NR2C1; CSDC2; FOXO3; CEBPA; ZBTB3; ZNF217; ZNF91; EZH1; ZNF665; CBX7; L3MBTL1; ZNF33B; BPTF; ZNF606; ELF2; KLF11; ZNF688; ZNF362; FOXN1; ZKSCAN3; DYRK1B; ZNF43; HOXB1; ZNF345; HDAC5; TBX21; NCOA2; GLI2; ZFPM2; HOXD3; ZNF500; NFATC3; ZNF446; ZNF76; GON4L; RORC; HOXD1; CDIP1; ZNF415; TSHZ2; KLF3; ZNF302; TRIM22; ZNF177; NR5A1; ZNF34; CRX; PRDM14; ZNF573; HINFP; TCEA2; STAT2; NR1I3; ELF4; TCF7L1; ZNF223; ZSCAN18; CEBPD; BRF2; ZNF467; ZNF506; THRB; SIX6; YBX2; ING4; LPIN2; ZNF219; INSR; PCGF3; ZNF778; MXI1; ZNF623; ZBTB44; ZNF224; ZNF75D; VENTX; BCL6; MZF1; ZNF253; LHX3; RERE; ZNF257; KLF7; MNDA; ZNF141; ZNF423; ZFHX2; YEATS2; ALX3; TLE4; ZNF329; ZNF93; BAZ2B; TULP2; ZNF667; ZXDC; MNT; TFAP2A; CNOT2; ZNF195; HIF3A; MED12; TXNIP; MYCL; ARNT; ZNF133; TP73; ATF2; ZNF510; ZNF701; ETV2; GTF2IRD1; PKNOX1; ZNF44; ZNF112; ZMIZ2; ZNF571; HOXC4; INSM1; ASCL3; PHIP; FOXH1; THRA; ZNF334; ZNF84; KLF13; ZNF132; ZSCAN16; ZNF682; GBX2; EMX1; ZSCAN9; APBB1; IRF7; NCOA3; CHD2; ZNF304; ZNF675; ATF3; ID2; SCRT1; NFATC4; RBFOX2; ZNF358; BACH1; BCL11A; MXD3; RSF1; BNC2; CRTC1; PHF1; TRAK1; OVOL2; ZNF154; CARF; WIZ; CEBPE; SCAI; HOXB13; NR1H4; ZNF222; ZNF264; ZNF350; CREB3L2; HDAC9; HESX1; SRY; TAF5; ZNF711; ZNF136; ZMIZ1; ARID5B; SAP130; ZKSCAN7; ZNF611; ZIC3; ZNF24; EMX2; ZNF135; SOX2; HMG20B; MECP2; NHLH2; MYBL1; VAX2; ZNF254; RBPJ; ZNF671; ZNF273; ZNF268; DLX4; SOX3; ZNF140; BANP; MBD4; ZNF292; ZIM2; ATF7IP; ZNF235; KAT2B; ZNF337; ZNF155; THAP10; RXRA; TGIF1; ZHX2; ZNF208; ZNF239; ZNF12; ELF5; TCF7L2; GCM1; ZBTB20; WNT4; HSF4; TBX5; WT1; SIN3B; ZNF529; PKNOX2; NKX3-2; MAFB; DDX17; POU5F1B; BNC1; ZNF419; ZNF14; AR; E2F8; BARX1; ZMYM2; POLR3C; NFIL3; ZNF180; SOX13; FEZF2; ID4; SOX17; BRD8; IRF6; POU6F2; PBX1; GRHL2; JUND; GLI3; ZNF266; HMBOX1; HIPK1; NEUROG2; HMGN3; ASCL1; ZNF160; PRMT2; NR0B1; VPS72; MYT1; CHD9; MED14; SALL1; KDM5B; FUBP1; PDLIM1; JUP; ARID4A; MEIS1; ESR1; ARNT2; TSG101; CBX5; FOXO1; ZNF544; DLX5; TAL1; NEUROD1; ZNF211; TLE1; TCF25; TCF15; DDIT3; SMAD6; ZNF430; ATOH1; TRIM24; NANOG; ZBTB43; MYCN; LYL1; TRPS1; SOX18; FLI1; ARID3B; IRF1; FOSB; PHF20; ZNF532; LIN28A; EP300; GATA6; NR5A2; SND1; ARID4B; ZKSCAN1; OSR2; SMARCC2; NFE2; MAF; ZNF331; SIX3; TFEC; ST18; TULP3; CUX2; PFDN5; MEOX1; PEG3; BACH2; HLX; MED13; RBBP8; KLF9; FOS; SMARCA1; IRF8; CERS4; FOXE1; SSBP2; CARHSP1; TCF4; SNAI2; BHLHE41; VGLL4; PAX6; SSBP3; DMTF1; ARID3A; MYRF; CENPF; TCF7; JUN; ZSCAN31; TBL1X; SPDEF; ZBTB16; MECOM; IFI16; ZNF589; AFF1; ZNF107; TOB1; CREB1; TBX3; ZNF586; BASP1
Down-regulation 121 FOSL1; PUF60; RUVBL1; MYCBP; TFDP1; GTF2A2; FHL2; MYC; EGR1; C1QBP; MYBL2; PCBD1; DRAP1; HMGA2; GABPB1; RUVBL2; HDAC2; TBP; EGR3; PA2G4; PARP1; RBM14; WDR77; SFPQ; TCERG1; PPRC1; SUB1; YWHAB; HMGA1; CBFB; NOC2L; ENO1; MYBBP1A; ABT1; TSC22D2; RAN; ZBTB18; EDF1; CTNNB1; EED; EZH2; TRIM28; MED6; SMARCC1; FLNA; BMI1; SFMBT1; PITX1; HNRNPD; CARM1; NPM1; MTA1; UBP1; CENPB; ILF2; YAF2; CALR; TFAM; SMARCD2; TEAD4; NFKBIB; NELFB; NUP62; PRKDC; MLX; MTDH; PIR; PTRF; HDAC1; SF1; MED1; ZNF593; ORC2; BCLAF1; AATF; MED21; XRCC6; IRX5; HES1; ELK3; RUNX3; CRY1; ECD; RNF138; SMAD5; CEBPZ; TRIM32; BAZ1A; RNF6; PSMC3IP; EGR4; SREBF1; CCDC59; RBBP4; HOXB7; TRIB3; SATB2; BATF3; ELF1; JUNB; BHLHE40; TRIP6; CHD7; LEF1; HSBP1; ADRB2; VDR; CCNA2; FOSL2; CTR9; TRRAP; TGFB1I1; ETS2; NR2F2; LOXL2; IRF4; ETV5; TOX3; HOXC6; EGR2; SUV39H1