Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16319 Barasertib-hqpa GSE70138 MCF10A Human 24h 0.12uM EID0006
Types Number Response transcription factors
Up-regulation 21 TGFB1; HDAC9; KDM5D; NR4A2; TBX2; RUNX1; FOXF1; NR2F1; TRIP6; JARID2; NR2F2; FOXF2; EYA1; LOXL2; TRIM22; MEIS2; MECOM; ID3; MEIS1; BASP1; FOS
Down-regulation 25 ATF1; GATA4; HSBP1; HMGB3; PDLIM1; SIAH2; ASCL1; ELF5; CREB3L1; MAGED1; TGIF1; ATF5; SMAD1; ESR1; HOXC6; JUN; PGR; MYBL1; FOXL2; TXNIP; LEF1; GATA6; MAFB; TOX3; SUV39H1