Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16312 Vemurafenib GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 70 NFATC3; KLF13; E2F2; IKZF1; SSBP2; HOXB7; TBX21; KLF1; HOXB6; STAT2; TAL1; BAZ2A; HOXB5; NR1D2; BCL11B; PRKDC; BHLHE41; MNDA; ZNF83; MAFB; FLNA; CITED2; KLF3; RXRA; SMARCC2; ZEB2; TGFB1; PTRF; RARA; KLF9; BCOR; ZBTB38; PLAG1; MED1; SALL2; SERTAD2; FOXO1; FOSL2; HOXC6; GATA3; BACH1; ERBB4; SMAD7; RORA; TERF1; HOXB2; BAZ1A; BNC2; HEY2; ZNF160; IRF4; MAF; SOHLH2; RUNX3; FLI1; FOXG1; LEF1; ESR1; TOB1; ID2; EGR3; ADRB2; TXNIP; POU2AF1; ZFP36L1; ASCL1; CD3D; TWIST1; THAP11; KDM5D
Down-regulation 25 TDP2; BRIP1; ST18; PHF1; TSC22D1; BLM; NR2F6; HDAC9; ARID4B; TFAP2C; OSR2; ID1; HEY1; HIRA; JUND; ELF5; PTTG1; TP63; CEBPB; TRIM24; LITAF; ATF3; MEIS2; WWTR1; FOS