Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16311 Vemurafenib GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 42 KLF11; ZNF117; NFATC3; IRF9; KLF13; ZNF239; ILF2; IRF8; ZBTB20; ZNF512B; ZNF331; KLF6; TCF4; ZFPM2; ERBB4; AEBP1; EMX2; NFATC4; HLX; ARNT2; TFAP2C; ZNF91; BACH1; BNC2; HIC2; ZNF232; ZNF611; TCF7L2; CBFA2T3; APEX1; TRIB3; ZNF589; TWIST1; MEIS2; HOXB2; BCL11A; HLF; WWTR1; PEG3; TOX3; ZFP36L1; FOS
Down-regulation 21 BMI1; HOXA5; ARID4B; ZBTB38; SMAD7; JARID2; PURA; ASXL1; CTR9; MAGED1; EYA2; ELK3; PIR; KLF2; SATB2; SMAD6; NR2F2; BHLHE40; MECOM; ID1; SUV39H1