Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16303 Pd-0325901 GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 255 NFATC3; MEF2C; CALCOCO1; TRIM22; ZNF571; ZBTB3; IRF9; JUP; NR5A1; ZNF667; DYRK1B; BPTF; FOXO3; TSC22D3; ZNF224; ZNF362; HDAC5; MAML3; PRDM2; ZFPM2; SUPT7L; L3MBTL1; ZNF711; HBP1; MNT; CNOT2; PBXIP1; ZNF268; ZNF141; ZNF682; ZNF257; ELF3; ZNF331; ZNF471; ZNF208; ZNF112; MKL1; PAWR; MZF1; CSDC2; FOXO4; TEAD3; SREBF2; BTG1; MEF2D; CREBL2; ZNF234; ZNF304; HDAC9; ZNF223; KLF11; ZNF768; POU2F3; SOX12; ZNF81; ZMYM2; ZNF345; BCL6; ZNF573; BRDT; ZNF467; ZNF334; CBX7; OSR2; ZNF780B; AFF2; MYF5; ZNF117; SOX4; CDIP1; ZNF214; OVOL2; NCOA2; BNC2; MSX2; ZNF814; TSHZ2; VHL; ZNF350; IRF7; KLF13; SP110; TFAP2A; GCM2; PNRC1; ZNF749; TP63; HMBOX1; TRIM29; ZNF674; SOX2; RFX3; SOX3; THAP9; CUX1; ZNF80; ZNF225; ZNF10; ZSCAN31; ZNF492; AR; ZBTB44; GSC2; ZNF254; IRF6; SALL2; ZMYND8; ZNF675; SRCAP; SIM1; ING4; FEZF2; GCM1; NCOA3; TCF4; ZNF155; SP100; FOXN3; FOXO1; PKNOX2; ZNF695; ARID5A; ZNF415; SKIL; WNT4; ZNF440; ZNF407; ZNF529; ZNF157; CARF; MBD4; MAF; BARX1; TLE1; POU1F1; SCAI; SOX18; PAX4; MEIS2; CUX2; ZNF44; NR4A2; HESX1; ZKSCAN7; SNAI2; EMX2; PPARGC1A; WT1; MYCL; CEBPD; MXI1; ZNF423; CREB5; MITF; EP300; KAT2B; ZNF165; REL; MDM2; AES; GLI2; MYCN; ERBB2; ZNF606; KLF4; ZNF493; NR5A2; RORA; ZFHX3; ATF3; SMARCC2; HOXD1; MED14; KLF5; TCF15; SOX5; ZNF623; WWC1; RBFOX2; NR1H4; PBX1; MEIS1; TCEB2; HIVEP1; ZNF131; FOSL2; MEOX1; RSF1; GATA6; TOX; BACH1; PDLIM1; TCF7L1; TCEA2; ZIC3; BAZ2B; BACH2; SMARCD3; ZNF512B; ZBTB16; ZNF611; CTBP2; INSR; ZNF12; ZNF43; TFAP2C; ARNT2; INSM1; TRIM16; NFATC4; CERS4; TBX1; ZNF91; ZHX2; ID2; ARID5B; SPDEF; ISL1; SIX3; BCL11A; PHF20; CITED2; TOB1; EHF; AHR; HIC2; CHD9; ZBTB1; NR4A3; TCF21; CBFA2T3; TCF7L2; TFEC; TXNIP; SOX17; TULP3; KLF10; PLAGL1; HMGN3; IFI16; ID3; CREB3L2; HLF; DLX5; PEG3; VGLL4; AEBP1; ZNF652; ADRB2; ID1; MECOM; SSBP2; CREB1; ZFP36L1; CREG1
Down-regulation 83 FOSL1; HMGA2; EGR1; CCNA2; EZH2; TFDP1; DRAP1; PUF60; HMGA1; MYBL2; FOXM1; SSRP1; CENPF; MYC; RUVBL2; SATB2; GMNN; BATF3; WHSC1; PTTG1; HMGB2; CALR; PA2G4; DNMT1; CDK2; NUP62; ASH2L; BRCA1; CHAF1B; PARP1; BMI1; BLM; ELK1; HMGB1; NPM1; ITGB3BP; PSMC3IP; RBBP4; GABPB1; BCLAF1; KMT5A; FOXD1; ETS1; DEK; TFAM; HLTF; ELK3; PSMC3; BAZ1A; CBFB; RAN; BAZ1B; ILF2; C1QBP; NFKB1; SAP30; MLX; TRIM28; ETV4; MAFF; HNRNPD; CTR9; CTNNB1; AGO2; MED1; RBM14; MTF2; HOXC6; ENO1; EGR3; SPEN; NFIB; SUV39H1; HOXC10; IRX5; PITX1; MYB; HSBP1; LEF1; WWTR1; MSX1; SOX9; EGR2