Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16294 Hg-5-113-01 GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 413 PRDM2; CALCOCO1; HBP1; ZNF117; TSC22D3; FOXO3; IRF9; CIR1; ERBB4; PBXIP1; BRWD1; KLF13; ZNF223; ZBTB17; CBX4; TLE4; ZNF195; ING4; PNRC1; HDAC5; NR3C1; ZNF75D; NFATC3; ZKSCAN4; FOXN1; DYRK1B; KLF11; PRDM14; HINFP; CBX7; ZNF141; CDIP1; ZBTB3; ZNF682; CREBL2; ZNF688; NCOA2; NFATC4; CHD2; ZNF573; GLI2; ZNF74; MZF1; RARG; SCRT1; ZNF415; EMX1; ZNF711; ZNF345; ZNF219; INSR; TCF4; PRDM10; TSHZ2; THRA; ZNF444; MXI1; ZNF350; CRX; NR5A1; MAPK8IP1; ZNF91; E4F1; FOXN3; ZSCAN16; NEUROG3; ZBTB44; THRB; ZNF235; CAMTA2; ZNF354A; DAXX; CSDC2; TCEA2; NR2C1; HOXB1; ETV6; ZNF154; ZNF34; VENTX; ZNF329; PIAS4; ZNF571; CEBPD; ZNF331; TULP2; ZNF667; MBD4; ZNF132; ZNF549; CBFA2T2; ZNF701; ZNF85; ZNF778; MAML3; ZNF665; ZNF224; ZNF174; CBX2; ZNF79; GON4L; ATF3; SP100; SRY; EZH1; ZNF165; MEIS2; ZXDB; HESX1; NR4A1; ZNF214; HOXB13; PIAS1; NAB2; KLF3; SALL2; SOX18; MED12; BHLHE41; ZNF227; HSF1; ZFP2; ZNF471; ZNF362; ZNF671; TFAP2A; FEZF2; SETDB1; SOX4; ZNF257; HIF3A; MYRF; PAWR; MEF2C; FOXH1; ZHX2; TAF1C; HIRA; GRIP1; ZNF500; TRPS1; ZNF225; NKX3-2; BTG1; RFX1; ZNF10; SOX21; SOX3; BACH1; ZNF175; TP73; ZNF222; IRF7; CAMTA1; SPI1; CEBPE; NKX2-5; ZNF654; BAZ2A; POU6F2; NCOA3; ZNF768; KAT2B; CUX2; GBX2; LIN28A; ZNF239; UBE2B; TLX3; ASCL3; ZNF33B; ZNF180; ZNF81; RXRG; ZNF623; ZNF254; GATA1; ZNF695; RAX; AR; BARX1; NR4A2; PAX6; RAD21; SIN3B; NR5A2; ZNF467; ZNF43; ARID5B; YBX2; L3MBTL1; ZXDC; SUPT4H1; SUPT7L; CBFA2T3; TEAD3; ZNF675; TBX21; LHX3; ZSCAN9; MNDA; SNAI1; PRDM9; SOX2; ZFP36L2; ZNF334; MED25; DLX4; HOXB8; HSF4; ST18; FOXE3; BACH2; ZNF112; ZIC3; NFATC1; NEUROD2; CARF; BRDT; ZNF304; KLF7; HNF4G; HDAC9; SP4; HMBOX1; ZNF80; BNC1; PHIP; ZNF155; SOX12; POU2F3; THAP9; ZSCAN18; TCF7L2; GSC2; NANOG; HOXD3; TAF6L; ZNF83; AFF2; ZNF510; ZNF613; TBX5; ZNF606; PROP1; ZNF253; EGR1; SRCAP; VHL; TFDP2; RARB; DDIT3; TERF2; ZNF177; ZNF133; FOXI1; GCM2; ZNF93; ZKSCAN8; ZNF674; TDP2; PHF1; ZBTB16; ZNF780B; FOXJ2; NEUROG2; TRIM22; HOXD1; ARNT2; NFIL3; SCAI; GRHL2; POLR3C; HIC2; SHOX; BPTF; PAX4; MDM4; ZNF536; KLF9; ZNF407; JUP; ZNF440; STAT2; PEX14; ZNF268; PRDM1; POU6F1; RFX3; BCL11A; LYL1; ARID1A; SKIL; ONECUT2; SSBP2; BANP; ZNF157; MED17; ATOH1; WT1; ZFHX3; ZFPM2; TRIB3; VPS72; MYBL1; IKZF3; MECP2; ATF7IP; OSR2; IRF6; ZSCAN31; ATN1; TCF7L1; SOX17; CREB3L2; POU1F1; DLX5; NHLH2; ZNF12; ZNF44; ZNF273; FOXK2; DEAF1; ZNF394; SSBP3; ARID3B; TWIST1; ZNF423; KDM5C; GATA6; TULP3; HEY1; NR1H2; TFAP2C; DBP; FLI1; MEOX1; BNC2; BCL6; RSF1; WNT4; AEBP1; ZBTB20; BRD4; SPEN; SOX5; KLF6; PBX1; ELF5; PEG3; ZNF544; ZNF589; CERS4; JUND; SP110; EP300; TLE1; VGLL1; YAP1; ZMYND8; EN1; CUX1; KMT2A; HLX; SMARCC2; NR3C2; SPDEF; ZNF532; CREM; ESRRG; ARL2BP; ERBB2; POU2AF1; ARID3A; ZNF611; TGIF1; TBX1; SOHLH2; RORA; NEUROD1; MEOX2; NFE2; FOSB; FOXF2; HOXB6; FOS; TCEA1; TGFB1; ZNF232; GFI1; KAT6B; TBX3; IRF8; NR1H4; SIX3; TOB1; TCF21; HAND1; ZEB1; ID4; INSM1; PBX3; SALL1; MEIS1; CREB1; ID2; TXNIP; TOX; TFEC; SPIB; DACH1; SATB1; ZFP36L1
Down-regulation 90 FHL2; FOSL1; MYCBP; TFDP1; PUF60; GTF2A2; NUP62; MYC; TP53; DRAP1; EDF1; RHOA; RUVBL2; ITGB3BP; RUVBL1; HLTF; PARP1; HSF2; RBM14; EZH2; NPM1; CCNA2; BCLAF1; UBP1; SFPQ; ZBTB38; PTTG1; MAGED1; FLNA; STAT3; BMI1; MED1; ENO1; PSMC3IP; HNRNPD; SMARCE1; CBFB; NFKB1; PIAS2; NCOA4; MLX; IRX5; PSIP1; ATF1; RNF4; PBRM1; RBBP4; C1QBP; RBBP7; NR2F2; SMARCA2; ADRB2; HES1; SUB1; BATF3; BAZ1A; ELK3; XRCC6; PRKDC; HOXA5; RAN; PURA; PITX1; SATB2; SREBF1; TRIM32; ZBTB18; PIR; HMGB3; BRCA1; BLM; JARID2; TRIP6; MTDH; CHD7; CTNNB1; MNAT1; HSBP1; CENPF; ATF5; ETS2; YWHAB; GTF3A; NRIP1; IKBKAP; NKX3-1; BHLHE40; WWTR1; SUV39H1; HOXC6