Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16293 Geldanamycin GSE70138 MCF10A Human 24h 0.04uM EID0005
Types Number Response transcription factors
Up-regulation 372 CALCOCO1; PNRC1; HOXA5; TSC22D3; HBP1; NR3C1; MZF1; CBFA2T2; ELF4; PBXIP1; ZNF33B; ZNF446; ZNF688; ZKSCAN4; EZH1; DYRK1B; ZNF611; CIITA; GATA3; ZNF160; ZNF606; ZBTB48; HOXD3; ZNF467; BAZ2B; BPTF; NR6A1; HOXB3; BARX1; GRHL2; CDIP1; SALL2; ZNF224; CBX7; NCOA2; ARID5B; ING4; CIR1; MECOM; RBPJL; BTG1; ESR2; MKL1; TP63; TSHZ2; HIF3A; TCF25; STAT2; TEAD3; ZFHX3; MEF2C; FOXH1; ZNF768; HOXD1; HINFP; ZNF44; AFF3; JUP; HEY1; MED25; HOXA4; ZNF219; CIC; GRIP1; ZNF500; OVOL2; EP300; NR5A1; LDB1; PHF1; ZNF76; ZNF671; SOX12; ZNF814; IRF7; TCF4; ZNF721; ETV7; CSDC2; TCF15; GLI2; ZNF423; SOX18; SOX17; CEBPA; TBX5; CHD2; WNT4; ALX4; TBX4; E2F2; RXRB; PBX1; TGIF2; PRDM14; SETDB1; POU2F1; HNF4G; HDAC5; PRDM9; ALX3; SOHLH2; HNF1A; ZNF444; NKX3-2; ZNF536; RFX7; HSF4; ZNF117; ZBTB3; RORC; KDM4A; THRB; ARID5A; VENTX; ZNF165; ZNF212; ZMYM2; ATOH1; ZBTB7A; ZFHX2; TLE2; ZMYND8; AFF2; MSC; MAML3; ZNF701; SOX13; MYCL; MECP2; RAX; ZNF362; ERBB2; ZHX2; CBFA2T3; IKZF3; MYF5; MED14; POU2F3; FOXB1; MAF; AR; ZNF75D; MXD4; ZNF135; MYOG; ZNF43; DAXX; ZNF254; TRIM22; ZNF665; ZNF778; TFEC; SPI1; PAX6; RXRG; ZNF154; IRF6; PRDM12; TFAP2C; NR0B1; ZNF358; TULP1; NAB1; TRIM29; ZNF331; L3MBTL1; EMX1; JAK2; CARF; ZNF350; CRX; ZNF304; NR5A2; PRDM10; ZBTB44; TP73; AIP; BCL11A; ZNF205; POU6F2; HIC1; CREBL2; HOXD9; ZSCAN18; DBP; HOXB1; IRF8; EVX1; SHOX2; CHD3; KDM4C; HOXD13; ZNF83; MDM4; HLX; ST18; GCM1; SMARCC2; PHIP; PAX9; AES; KAT6B; PDLIM1; EHMT2; MLXIPL; BANP; FOXA1; TCEA2; HOXA3; ZNF91; MAK; IRF9; ZNF345; HOXB5; SCRT1; TOB1; NEUROG2; ZNF214; SMARCD3; TONSL; SOX5; BCOR; ZNF646; SOX3; ESR1; MEF2D; HSF1; EPAS1; ZIC3; HESX1; ZNF544; CEBPD; FOXJ1; RARG; ZNF223; FEZF2; MEIS1; PRDM2; ZNF136; MXI1; GFI1B; PITX3; SIX6; GBX1; GLI3; SUMO1; PLAG1; ZBTB17; ZNF667; TERF1; ZNF711; ZNF85; ZNF74; SIAH2; IKZF1; SOX2; MEOX1; OSR2; SCAI; MNT; BCL6; MDM2; ZNF354A; BRWD1; ZNF580; ID4; HOXB2; ZNF264; ZNF682; TBX21; ZNF141; ZNF195; PKNOX2; APBB1; FOXN3; NHLH2; ZFPM2; TP53; ISL1; TOX; NAB2; PEX14; GATA4; NR0B2; RSF1; HOXC4; AEBP1; ZSCAN16; KMT2A; TRPS1; TFAP2A; BACH1; LIN28A; ZNF248; TBX1; FOXF1; BNC2; ARID1A; MBD4; BRD4; ZNF217; EN2; IRF1; KLF5; GATA6; ERBB4; HMX1; NFATC1; TCF21; ZNF623; CBX4; TCF7L2; ID2; FOXO4; TWIST1; ATF3; MEOX2; KAT2B; SPEN; SREBF1; TXNIP; DDIT3; ZSCAN31; HEY2; EHF; KLF13; NEUROD1; POU2AF1; CUX2; ZNF652; WT1; FOXO1; ZNF12; TULP3; PLAGL1; PEG3; LITAF; HMBOX1; NKX2-2; HOXD11; EYA1; MYCN; CITED2; MNDA; ARID4B; NR1H4; HMGN3; MYRF; ARNT2; ELF3; NANOG; FOXF2; NFATC4; SOX10; MEIS2; NFATC3; TLE4; SOX11; CTBP2; HMG20B; INSM1; BCL3; ZNF589; KLF11; TSC22D1; ZNF512B; FOXG1; BASP1; ZIC1; SSBP2; BHLHE41
Down-regulation 100 FOSL1; CCNA2; HMGA2; ADRB2; MYC; TFDP1; RUVBL1; EZH2; PSMC3IP; CHD1; DRAP1; NFIL3; EGR1; MYBL2; ETV1; DNAJC2; MYCBP; RUVBL2; XBP1; MLX; CBFB; RHOA; MED6; GCFC2; EGR3; TSC22D2; PPRC1; CRY1; ELK3; CHAF1B; NPM1; ITGB3BP; BLM; WDHD1; BRCA1; SMAD5; WDR77; RAN; ZBTB38; ENO1; C1QBP; ARNTL2; YWHAB; RBM14; BCLAF1; EGR4; SUB1; SSRP1; HNRNPD; TAF9; GABPB1; PA2G4; SMARCA5; RNF138; ECD; ZBED4; TAF9B; EED; ZNF146; CCDC59; JUNB; BATF3; TRIM32; FOXD1; HMGB1; NKX3-1; JUN; GATAD2A; KLF2; SUV39H1; SAP30; BMI1; TEAD4; CHD7; ING3; ETS1; BAZ1A; STAT3; SFPQ; ZBTB18; ETV5; CALR; EGR2; NR2F2; HMGB2; HLTF; PTTG1; STAT1; JARID2; LEF1; HOXC10; SOX9; PURA; KLF9; IKBKAP; STAT5B; TCFL5; PPARG; PUF60; FOS