Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16292 Geldanamycin GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 274 GATA3; CALCOCO1; HOXA5; PNRC1; NR3C1; TSC22D3; ZNF611; MZF1; ZNF160; SALL2; HBP1; HEY1; PBXIP1; ID4; BPTF; STAT2; CEBPA; TLE2; MXD4; ZNF721; ZNF91; ZNF536; ELF4; DYRK1B; GRHL2; EZH1; NCOA2; IRF9; HDAC5; ZNF117; ZNF688; MDM2; ARID5B; HOXB3; ZNF446; ZBTB44; HNF4G; ZNF665; ZNF33B; ERBB2; ZNF224; PRDM2; EPAS1; BAZ2B; DLX4; HIF3A; ZNF701; ZNF467; RXRB; ZNF44; ZNF768; AES; CBX7; TEAD3; BAZ2A; HOXB2; KDM4A; ING4; BARX1; HOXB5; KLF3; ZSCAN31; RARB; ZKSCAN4; OVOL2; SREBF2; ZNF606; TCF25; NCOA3; ZNF219; BTG1; TBX10; RARG; PHIP; ZNF362; ESR2; MEOX2; SOX12; TBX4; TBL1X; EP300; FOXF1; SIX3; CDIP1; RING1; ZNF500; PAX6; ZNF345; ZNF778; EYA1; ARHGAP35; LITAF; MNT; PRDM14; NFKB2; MED12; JUND; ZSCAN18; TSHZ2; ZNF444; SPI1; ZNF587; ZFHX3; ZNF264; NR5A1; THRB; HINFP; SRCAP; CSDC2; TCF21; ERBB4; ZNF135; NFATC1; HOXD1; LZTR1; ZNF580; CIR1; MYF5; MED23; TAF7L; TP63; EBF2; TSG101; SIRT2; HOXD13; TOX3; ZNF358; MYCL; MECP2; NHLH2; ATOH1; TXNIP; TBX2; PDLIM1; TP53; HOXA4; PBX2; CHD2; TGIF2; APBB1; THRA; TCEA2; SOX21; ZNF165; ZNF83; IRF7; ZNF652; PHF1; AR; ZBTB7A; REPIN1; NFAT5; NR0B1; TRIM29; MEOX1; TRPS1; NAB2; PGR; PBX1; BANP; NPAS2; ZNF205; TRAK1; FOXN3; INSR; GFI1B; YAP1; TRIM22; SOX18; WNT4; ESR1; OSR2; SMARCC2; HEY2; ZNF226; MXI1; ARNT; DDX17; CBFA2T3; CREBL2; TCF15; MAZ; SOX3; HMGN3; LDB1; KLF5; ZKSCAN1; TFCP2L1; MEIS2; KLF13; RBL2; NKX2-2; MEIS1; ZNF512B; ZNF248; RUNX3; SOX13; SIM1; KAT2B; NAB1; JUP; FOXO4; SMARCA1; RNF10; ZBTB20; BCL11A; NCOA1; CUX1; PFDN5; TRIM16; ZHX2; NR1I2; TBX21; MECOM; HDAC9; ZSCAN16; KDM5B; EHF; RORA; TCF7; ELF3; CDYL; DBP; FOXA2; DLX5; BRD8; HOXB6; BRD4; TOB1; MAF; HMBOX1; PLAGL1; MITF; CREM; FOXA1; INSM1; SALL1; CITED2; SOX17; BCL6; MYRF; IRF6; BCL3; NR3C2; RSF1; BNC2; TGFB1; ZNF415; ARID4B; TAL1; RXRA; FOXF2; ZIC1; NR1H4; NR4A1; TCF4; FLI1; TFAP2C; PEG3; DACH1; ST18; TOX; HMG20B; ZNF423; NFATC4; PIR; ARNT2; ATF3; MNDA; SSBP2; NR4A2; TLE4; CRYM; BASP1
Down-regulation 110 FOSL1; HMGA2; ADRB2; CCNA2; MYC; RUVBL1; EZH2; PSMC3IP; TFDP1; FHL2; MYBL2; DRAP1; EGR1; ZNF473; NUP62; NFIL3; PPRC1; GMNN; WDHD1; TAF1A; BRCA1; CHAF1B; CHD1; WDR77; PMS1; TFAM; RBL1; RUVBL2; BLM; MED6; RNF138; DNAJC2; NFX1; TAF9; ETV1; MLX; BAZ1A; CDK2; JUN; SUB1; PA2G4; TRIM27; ITGB3BP; DR1; NKX3-1; POLR3F; HMGB1; TSC22D2; CBFB; RBM14; GABPB1; ZNF200; CHD7; BCLAF1; GCFC2; PREB; TEAD4; YEATS4; RAN; SMARCA5; CCDC59; ZNF107; ZNF267; RB1; ETV4; FOXM1; TGS1; SMAD1; CENPF; JUNB; HNRNPD; C1QBP; YWHAB; ETV5; CEBPZ; HMGA1; CRY1; SSRP1; ZNF593; GTF3A; ELK3; XRCC6; ACTL6A; SFPQ; EGR3; SUV39H1; ENO1; RNF6; NFIB; LEF1; ING3; ID2; XBP1; HMGB2; STAT1; PTRF; KLF6; TRIM32; ING2; SAP30; CEBPG; JARID2; ZFP36L1; ZNF22; PPARG; MYBL1; ZBTB18; CREB1; TCFL5; EGR2