Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16290 Geldanamycin GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 432 CALCOCO1; PNRC1; NR3C1; HOXA5; HBP1; MZF1; PBXIP1; ZNF91; EZH1; ZNF224; ZNF536; BPTF; ARID5B; ZNF665; CBX7; SALL2; HIF3A; PAX6; ID4; PPARA; ZNF606; DYRK1B; MEOX1; ZNF611; ZNF136; TSC22D3; TSHZ2; EP300; ZKSCAN4; BTG1; CREBL2; PHIP; GATA3; CDIP1; HOXB3; HOXA4; NR6A1; ZNF688; ZNF33B; ZNF135; ZNF264; BAZ2A; TXNIP; ZSCAN9; TBX6; ZNF223; CBFA2T2; IRF9; HOXB2; PKNOX2; GRIP1; ZNF160; PRDM2; DLX4; ZFHX2; NCOA3; AES; TBX4; BAZ2B; SIX3; ZNF219; THRB; RBPJL; ING4; LHX3; ZNF446; IKZF3; ETV3; ZNF768; TGIF2; ZNF221; ZNF117; ZKSCAN8; ZNF165; HEY1; PRDM14; ESR2; HMBOX1; ZXDB; RXRG; ZNF362; SIRT2; PRDM9; HDAC5; ZNF500; GLI2; RORC; ZNF778; TFAP2A; RING1; IKZF2; ZNF701; ZNF444; NR5A1; HOXA6; CEBPA; CIR1; ZNF155; TBX5; AFF3; CHD2; IRF6; SPI1; ZNF345; THRA; EPAS1; CRX; ZNF671; ZNF667; ZNF133; ZNF669; ZHX2; ZNF304; TULP2; ZNF484; AFF2; MED12; ZNF154; L3MBTL1; ELF4; TBX10; LZTR1; ZNF652; MAFK; SOX18; EBF2; ZNF816; ZNF132; TLE2; TFEC; CREB3L2; STAT2; SMARCA1; HNF4A; CSDC2; TLX1; RXRB; GATA1; ZNF586; ZNF394; ATOH1; ZNF44; GRHL2; IKZF4; ERBB4; SOX13; TCEA2; NPAS2; ALX3; ZNF423; DBP; SOX17; ESRRB; VENTX; SOX2; CARF; MED23; FOXE3; ONECUT2; POU3F4; HOXA3; SETDB1; ZNF331; POU6F2; NHLH1; MYF5; LITAF; FOXH1; HNF4G; BARX2; MED13; CCNT1; ZIM2; ZNF175; HDAC9; CBFA2T3; GFI1B; SOX1; SRCAP; ZBTB44; TULP1; TCF4; KDM5B; HOXB5; ZSCAN31; PAX8; JUND; ZNF814; BNC2; MED25; KDM5C; SREBF2; PBX1; HINFP; ARID5A; MEIS2; ZFHX3; MYCL; TEAD3; ETV7; PRDM12; ONECUT1; ZNF440; TSG101; HIVEP2; SMARCC2; HOXD9; RARG; MSX2; GTF2I; ZNF253; ZNF141; CCNH; MYOG; ZNF83; POU2F3; POU1F1; ZNF675; CIITA; MLXIPL; ZBTB7B; PPP1R13L; ZNF587; HOXD3; ZNF544; ZNF573; ZIC3; ZNF248; SOX12; FOXF1; GBX2; ZNF350; JUP; ZNF571; ARID3B; ZNF254; ZNF711; FEZF2; ZNF43; TRPS1; MNT; HOXD1; ZSCAN18; SUMO1; TRIM29; KAT8; SUPT4H1; TULP3; ZNF721; MECP2; SCAI; TP63; DCC; WNT4; NHLH2; APBB1; ZNF214; GBX1; ZMYND8; MAML3; SHOX2; ZBTB43; NEUROG2; TBX21; MKL1; TFDP2; ERBB2; PHF1; E2F5; RARB; ZKSCAN1; SUPT3H; MDM2; OVOL2; ZNF292; ZNF157; ZNF358; BRWD1; ZNF225; MEIS1; ARHGAP35; IKZF1; MEF2D; ZNF506; ZNF177; TCF15; BARX1; PBX2; EYA1; MKL2; FOXN3; ARID3A; ZNF257; KLF3; NR0B1; MAK; SRY; SOX3; ISL1; CERS4; JAK2; DLX5; NFIX; TRAK1; ZNF112; ZNF93; NR0B2; FOXF2; SIM1; TLX3; NCOA2; ZSCAN16; NEUROD1; DDX17; PEG3; TP73; NFE2L1; PDLIM1; VGLL1; YBX2; CHD9; ZNF426; CSDE1; TBX3; ZNF85; ZNF467; ZNF334; HOXB1; ZNF682; ZNF415; PEX14; BANP; CNOT2; TCF25; CDYL; TFAP2C; KAT6B; MXI1; MEF2C; KLF13; NFAT5; LDB1; NR5A2; LIN28A; STAT6; ZNF75D; CITED2; TCF7L1; TULP4; TBX1; INSM1; TRIM22; FOXA1; ZNF34; ST18; ZKSCAN7; RBL2; AEBP1; MECOM; BNC1; BRD4; FOXO4; INSR; TCF21; MEOX2; RBPJ; PIAS4; ZNF148; SSBP2; TCF7; RBFOX2; ZNF12; ZNF623; ZNF430; ELF5; HMX1; ESR1; RSF1; ATF3; OSR2; PITX2; ZBED2; NR4A1; NFATC4; NR1D2; SOX10; STAT4; PEX2; ZNF302; BBX; MITF; BCL6; HEY2; PCGF2; BCL11A; ZIC1; KAT2B; NR1H4; FOXO1; ZEB1; PRRX1; ZFPM2; TAL1; TLE4; HIC2; ARID4B; MNDA; NKX2-1; CUX2; CRYM; EN1; PLAGL1; GATA6; MAF; ZNF512B; IRF1; ARNT2; EMX2; POU2AF1; ZBTB20; PBX3; BHLHE41; VPS72; FLI1; BACH2; CREB1; NFATC3; MYRF; TRIB3; HOXB6; HMG20B; FOS
Down-regulation 120 FOSL1; TFDP1; ADRB2; MYC; CCNA2; EZH2; FHL2; PARP1; RUVBL1; MYCBP; EGR1; PSMC3IP; TCERG1; RHOA; NUP62; DRAP1; NRIP1; MYBL2; NFIL3; CHAF1B; FOXM1; RNF138; BRCA1; BAZ1A; DR1; BIRC2; HMGA2; DNAJC2; GCFC2; PA2G4; SF1; ELK3; C1QBP; CRK; PMS1; SSRP1; TBPL1; RUVBL2; ARNTL2; PPRC1; CBFB; ENO1; SFPQ; NOC2L; NPM1; RAN; CDK2; GMNN; BLM; RBBP4; HMGA1; CTR9; RBM14; ZBTB24; RBL1; EGR3; WDR77; MLX; HNRNPD; ITGB3BP; HMGB1; TRIM28; SMARCA5; RNF4; HOXA10; RNF14; CENPF; GABPB1; SUB1; CRY1; SAP30; ZNF281; YWHAB; RNF6; ZNF107; PSIP1; NFKB1; NKX3-1; HLTF; YBX1; BMI1; RBBP8; DNMT3B; XBP1; EDF1; MNAT1; ZBTB18; FOXD1; CHD7; GTF3A; DMTF1; CTNNB1; PTTG1; TSC22D2; PRKDC; SMAD1; BCLAF1; VDR; STAT3; SUV39H1; BATF3; HMGB2; ING2; EYA2; TRIM32; ID2; CEBPG; IRX5; MYB; HOXC6; SATB2; KLF2; KLF6; PUF60; TCFL5; PPARG; STAT5B; EGR2; IKBKAP; LEF1