Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16289 Geldanamycin GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 294 CALCOCO1; HOXA5; GATA3; NR3C1; PNRC1; PBXIP1; PPARD; ELF4; TSC22D3; MZF1; HBP1; EZH1; PRDM2; TP63; CBFA2T2; ZNF33B; ZNF160; BAZ2B; ZNF536; CBX7; GLI2; ZNF224; BAZ2A; DYRK1B; ZNF91; CEBPA; BPTF; PAX6; GRHL2; ZKSCAN4; SIRT2; ZNF117; ZNF223; SMARCA1; ZNF606; NCOA2; CREBL2; ZNF580; PRDM14; ZNF175; ZMYND8; PHF1; TCF7; LHX3; CREB3L2; CHD2; ZNF665; MECP2; HOXA4; ARID5B; THRA; ZNF248; TRPS1; ZNF611; ING4; ZBTB44; MKL2; ZNF133; NR1H2; NR5A1; HEY1; GRIP1; JUP; ZSCAN18; MXD4; NHLH1; ZNF446; HOXB3; HOXB2; TUB; TBX4; WNT4; EP300; ZNF83; BBX; ZNF444; HDAC5; SOX21; STAT2; IRF9; ZNF671; RARG; ZNF292; RBL2; LDB1; ZNF721; ZNF44; RXRB; ZNF778; ZNF331; CIITA; CCNT1; ZNF135; TEAD3; TCF25; SP100; DBP; GLI3; SALL2; AFF2; ESR2; TRIM22; RARB; ARID5A; PHIP; KAT2B; MDM4; CBFA2T3; AES; MDM2; TCF15; FOXJ1; TRIM29; TSHZ2; ERBB2; SRCAP; HSF4; OVOL2; AR; ZNF304; CDIP1; IRF5; HIVEP2; ZIM2; GCM1; RORC; ZNF362; ZNF264; TBX19; ZNF587; ZMYM2; PDX1; ZNF688; BARX1; ZSCAN31; HOXD1; HIF3A; HDAC9; DEAF1; BCL11A; ATOH1; OSR2; ATF1; TCEA2; SKI; TERF1; MEOX1; ZNF287; MED23; ZNF506; IRF6; MEIS2; MYOG; SMARCC2; ZNF350; TP53; TFAP2C; NHLH2; ZNF345; KDM4C; APBB1; ZNF177; TXNIP; RAX; KLF13; ID4; EYA1; TFDP2; CSDC2; SSBP2; CIR1; MKL1; PFDN5; CARF; SPI1; SIM1; CUX1; NKX3-2; ZNF432; BASP1; SOX3; L3MBTL1; ZNF667; LYL1; TULP1; HOXB5; ZNF219; ZNF226; SOX18; EPAS1; MAF; MNT; EBF2; ZHX2; HMX1; ZNF358; ZNF85; RERE; ZNF467; NR0B1; TP73; LITAF; BRD4; NR0B2; ZNF500; BTG1; FEZF2; KLF3; SOX2; ZNF75D; DLX5; SPEN; SP110; NAB1; SREBF1; TFAP2A; RXRA; TFEC; HR; ZMIZ1; TCF4; VGLL1; ZNF43; PAWR; CBX4; STAT6; ERBB4; TBX1; CRYM; RORA; FOXO4; NFAT5; ZBTB20; TLE4; ST18; PBX1; PEG3; ELF5; TOB1; ZNF415; MEIS1; DDX17; PDLIM1; HMBOX1; TOX3; FOXA1; HDGF; SMARCA2; HMGN3; ELF3; MEOX2; ID3; TCF7L1; BNC2; SPIB; FOXC1; DDIT3; CITED2; CREM; IRF7; TOX; SHOX2; ZNF512B; PLAGL1; NR1D2; KDM5B; HEY2; SOX10; KLF5; ZNF711; TBX3; ARID4B; FOXN3; TCF7L2; HOXB6; BACH2; NR4A2; EHF; AEBP1; SOX17; MXI1; INSM1; ARNT2; TLE1; NFATC4; TGIF1; HMGB3; BCL3; ESR1; HMG20B; POU2AF1; TSC22D1; ASCL1; CREB1
Down-regulation 128 FOSL1; CCNA2; HMGA2; ADRB2; TFDP1; MYC; EZH2; RUVBL1; EGR1; NFKBIA; PSMC3IP; PPRC1; MYBL2; DRAP1; TAF1A; PARP1; WDHD1; BRCA1; NUP62; CHAF1B; PMS1; KMT5A; WHSC1; CBFB; TSC22D2; ZNF473; CDK2; C1QBP; RBL1; PA2G4; TAF9; BLM; DNAJC2; KLF6; CHD7; ORC2; BIRC2; JUN; SMARCA5; CRY1; RNF138; ETV1; NELFB; SF1; NFIL3; WDR77; TBPL1; PREB; FOXM1; ZNF593; ELK3; ZBTB18; TTF1; SMARCA4; TEAD4; GCFC2; MED6; BATF3; RBBP4; PLAGL2; TFAM; E2F3; RUVBL2; SSRP1; NPM1; HNRNPD; BAZ1B; ZNF200; ZBED4; ERF; GABPB1; CENPF; ETV5; NFYB; RRN3; BAZ1A; RB1; NFYA; ZMYND11; TBL1XR1; AATF; EGR3; ARNTL2; GATAD2A; YWHAB; RNF14; CTR9; GTF3A; CBX3; RNF4; PRKDC; HOXA10; CCDC59; TAF9B; ZNF146; SATB2; NKX3-1; RAN; SUB1; RBM14; ZNF22; HMGB1; KLF2; CEBPG; RBBP8; ZNF281; HMGB2; SAP30; HOXC10; SUV39H1; PURA; TRIP6; PTRF; PITX1; MTA1; NFE2L3; SFPQ; THAP11; HES1; HOXC6; SNAI2; PTTG1; PPARG; MAFB; EGR2; LEF1; TCFL5; SATB1