Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16288 Geldanamycin GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 290 CALCOCO1; PNRC1; HOXA5; NR3C1; HBP1; PBXIP1; ZNF611; ZNF160; TSC22D3; EZH1; IRF9; EP300; MZF1; GATA3; ZHX2; NCOA2; ZNF536; RING1; NR1H2; BARX1; KAT6A; ARID5B; ZNF91; SIRT2; SALL2; CBFA2T2; NCOA3; PRDM14; MECP2; ZNF606; MXD4; HOXB2; HEY1; MDM2; AES; CBX7; ZMIZ1; SHOX2; ZNF665; TEAD3; MBD1; JUND; TRIM29; BPTF; ELF4; LITAF; ID4; ZNF44; DYRK1B; CREBL2; LHX3; ZNF500; SOX4; KLF1; ZNF721; ZNF135; SOX2; ZSCAN31; STAT2; ZNF224; NR5A1; ZNF446; ERBB4; ZSCAN18; TRPS1; PHF1; PRDM2; ZNF117; MYF5; CDIP1; ZBTB44; WNT4; THRB; ZKSCAN4; HIF3A; ZNF165; GCM1; ATF1; SRCAP; MED12; TSHZ2; TBX10; RORC; CDYL; TXNIP; ZNF467; IKZF3; TFDP2; HDAC5; AFF3; TBX4; ING4; INSR; RXRG; NFE2L1; ZNF154; CIR1; TCF7L2; ZNF223; GFI1B; POU1F1; PHIP; E2F2; TOB1; ALX3; PEG3; ZNF350; TLE2; HOXD1; CRX; HOXB3; ZNF688; TUB; OSR2; HOXB5; ZNF667; GRHL2; RARG; TP63; ZNF268; KLF13; MED13; KLF3; ESR1; TERF1; ZNF444; SOX13; ZNF331; KLF5; ATF2; SOX18; ZMYND8; ZFHX3; CSDC2; ZNF345; ZNF133; DDIT3; ZNF423; HOXA4; TCF15; PKNOX2; ZNF214; RARB; SOX3; MEF2C; GLI2; FEZF2; PBX1; MAML3; ERBB2; CHD2; ARID5A; DBP; TGIF2; BAZ2B; VENTX; HOXA3; TFAP2A; TLX3; AR; EVX1; TP73; ZSCAN9; SPI1; NFE2; L3MBTL1; DLX4; RBPJ; HDAC9; POU4F2; CARF; ZNF264; BRD4; ZNF362; ATOH1; TBX21; ST18; HSF4; OVOL2; NPAS2; GATA1; MEIS2; ZNF358; TCEA2; TRAK1; ZNF532; DLX5; JUP; CBFA2T3; EPAS1; TFAP2C; HEY2; ARNT; ZNF219; MYCL; ZNF587; TBL1X; ZBTB7A; MYOG; BBX; ZNF257; ZNF415; ZNF682; ZNF112; PDLIM1; NR0B1; HMBOX1; ZNF711; SIX6; HOXD3; BTG1; SMARCA1; ZIC3; DAXX; KAT2B; PRDM12; E2F5; TCF7; SOX17; RYBP; TCF4; LDB1; ZIC1; TAL1; ZNF148; MEIS1; SOHLH2; SMARCD3; FOXO4; CHD9; SP140L; MXI1; MNDA; CUX2; BCL6; TRIM22; FOXA1; PEX2; NFATC1; TCEA1; ZNF652; RBFOX2; FOXJ1; TOX3; RXRA; MECOM; BNC2; RSF1; IRF8; IKZF1; BHLHE41; HOXD11; CERS4; BCL11A; TRIM16; FOXF2; MYRF; NKX2-2; TOX; PAX6; NFATC4; HMGN3; ZNF217; FOXF1; TBX3; TCF7L1; IRF6; IRF1; PIR; ZNF512B; ZNF589; MAF; ZEB1; ARNT2; NR4A2; ID1; SSBP2; TGFB1; PBX3; HOXB6; ZFP36L1; ID3; KLF11; ATF3; NFATC3; SPDEF; WT1; POU2AF1; ASCL1; HMG20B
Down-regulation 117 FOSL1; ADRB2; MYC; FHL2; HMGA2; CCNA2; EZH2; TFDP1; EGR1; RUVBL1; ETV1; PSMC3IP; PPRC1; FOXM1; MYBL2; VGLL4; DRAP1; NFIL3; BRCA1; PA2G4; SSRP1; CENPF; CHAF1B; NPM1; NUP62; DNAJC2; BLM; MED6; SMARCA4; ORC2; TRIM28; RUVBL2; BRPF1; EGR3; CBFB; GMNN; NELFB; SMARCC1; DDX54; VDR; TFAM; MLX; ELK3; ENO1; CCDC59; C1QBP; BAZ1A; RBBP4; RBM14; WHSC1; GTF3A; HOXC6; RAN; HMGA1; NOC2L; RBL1; UBE2I; RNF138; PTTG1; FOXD1; GABPB1; RRN3; HMGB1; FLNA; CEBPZ; TAF1A; RNF4; BCLAF1; ZNF200; UBP1; RNF6; BRD7; HSF2; PREB; YWHAB; ING3; EED; ZBED4; ITGB3BP; PMS1; TTF1; ECD; SAP30; MED1; POLR2A; CEBPG; ZNF593; CTNNB1; RNF14; ZBTB18; HSBP1; RBPMS; SUV39H1; HNRNPD; BATF3; TRRAP; HMGB2; SFPQ; PTRF; TRIM32; ING2; KLF6; BMI1; CBX3; SUB1; HLTF; JARID2; LEF1; MYB; NR2F2; PPARG; ZNF22; SATB2; PUF60; TCFL5; STAT5B; EGR2