Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16282 Radicicol GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 263 EZH1; ZBTB43; KDM5A; CALCOCO1; ZNF136; HBP1; CIR1; CEBPA; NFE2L1; PHF1; MAFG; NCOA3; GATA3; BTG1; ZNF44; NCOA2; TMF1; TDP2; ZNF14; BRD2; PHIP; ZNF394; TFDP2; EP300; ZNF85; ZNF222; DDIT3; TXNIP; HCFC2; ATF4; SIRT7; JAK2; ZNF274; ZBTB40; CRK; ZNF79; NR1H2; RLF; E4F1; ZNF117; SIN3B; BRF2; BBX; ATF3; MED23; RNF10; ZNF12; NR0B1; ARID5A; HINFP; BACH1; TRIM33; MXD4; PHF20; SAP130; ZNF8; ERBB4; RYBP; TFE3; INSR; ZSCAN31; KAT6B; BPTF; ZNF24; PIR; ZNF264; ZNF43; ZNF430; ZNF688; NFE2L2; HTATIP2; CBX7; NCOA1; ZNF91; RBPJ; PBXIP1; BANP; JUND; ZNF175; ATF7IP; ZBTB11; RCOR3; MDM2; TOX4; KDM2A; TRAF6; ZNF148; ZNF304; HOXB2; PAX8; ID4; NR3C2; RXRB; KLF13; KDM5B; POU2F1; CDIP1; ZNF350; ZNF189; ZNF195; MXD1; KDM4C; ARID4A; PRDM14; MED13; ZNF629; ZFX; GON4L; ZNF292; HDAC5; ZSCAN16; SREBF1; CASZ1; SOX21; ING4; ZBTB44; KMT2A; ZNF506; ATF2; RBM39; ZNF467; ZNF426; TSG101; LDB1; SUMO1; KLF3; ZNF133; ELF4; BRD4; TRIP11; NRBF2; PRDM2; ZNF23; EMX1; ZNF184; MECOM; SP140; E2F6; UBE3A; MED21; UBE2B; SIRT2; PIAS1; ZNF665; ZKSCAN4; ELF5; ZNF654; ZNF415; ZKSCAN1; ZNF652; CBX6; SP3; ARID3B; VENTX; SIX1; TFAP2C; SNAI1; LPIN2; CBFA2T3; SP2; BRWD1; TEAD3; ELF2; CEBPG; CLOCK; ZNF253; ZBTB17; ZNF331; ZNF257; IRF7; ZBTB7A; ZNF611; MYNN; RNF141; SUPT4H1; CTR9; TAF7; PTRF; ZNF165; NFATC1; CREBL2; CBX4; WWP1; TWIST1; DAXX; ZFHX3; MXI1; TSC22D4; ZNF711; ZMYND8; COPS2; MED17; ZNF267; TERF1; BCL11A; EPAS1; ZNF423; HOXD3; PIAS2; RSF1; TRPS1; SALL2; TBX21; HMBOX1; NFAT5; ARID4B; ZNF273; ZNF93; SHOX2; SMAD2; TRIM29; KLF10; ATF5; CITED2; ZNF345; NR1D2; CUX1; RREB1; CREB1; NCOA6; TCF7; DMTF1; FOXJ3; TULP3; CREB3; CERS4; KAT2B; FOXC1; CSDE1; IRF9; HOXD1; NR2F6; FOXO4; ACTL6B; HIPK1; KLF11; TBX2; TBX3; IRX5; TRIM16; MNDA; SERTAD2; MEOX2; EMX2; PAWR; TAL1; LITAF; DLX5; IRF1; SIX2; WT1; HEY1; TOB1; BCL3; ESR1; KLF2; OSR2; KLF4; TCF4; BHLHE41; MAF; PBX1; NFATC3
Down-regulation 124 CCNA2; MYC; TFDP1; DNMT1; RUVBL1; ADRB2; NFKBIA; C1QBP; SMARCC1; CDK2; VGLL4; HMGA2; EZH2; PA2G4; MYBL2; EGR1; PARP1; RBBP4; NOC2L; MYBBP1A; WDR77; RUVBL2; FOXM1; CBFB; SF1; NONO; RBL1; SSRP1; APEX1; PRKDC; RAN; HMGB3; FOSL1; BAZ1A; NPM1; TRIM28; GTF3A; MYCBP; CHD7; NFKB1; NRIP1; PPRC1; SMARCA4; HNRNPD; GMNN; CENPF; HDAC6; ATF1; PMS1; WHSC1; SLC2A4RG; ZMIZ1; TCF21; ZNF692; HES1; CBX5; MLXIP; SMARCD2; WDHD1; ZBTB16; CEBPD; KAT2A; HMGB2; YEATS4; GCFC2; XRCC6; ITGB3BP; ZNF551; PTTG1; RB1; ILF2; TBL1XR1; PRPF6; TEAD4; PITX2; ZFP36L1; TAF9B; BHLHE40; NR2F1; TAF1D; ZBED4; AHR; ENO1; BLM; CBX3; HDAC1; RBBP7; BMI1; CDK8; ACTL6A; CALR; TOX; ZBED2; HMGB1; ELK3; RBPMS; TTF2; STAT6; TGFB1; PQBP1; CTNNB1; EGR3; RBM14; SUV39H1; FOXF2; ZFP36L2; NR2F2; MTA1; HLF; TRIP6; ZNF22; FLNA; EGR2; MYBL1; IKBKAP; TCFL5; AEBP1; HMGN3; SATB2; NKX2-2; ID3; ZFPM2; LEF1; SNAI2