Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16279 Withaferin-a GSE70138 MCF10A Human 24h 0.37uM EID0005
Types Number Response transcription factors
Up-regulation 47 ADRB2; KDM5A; VGLL4; KDM5D; ZBTB20; KLF2; AES; TERF2; PAX5; TRIM16; PBXIP1; PSMC3; SMAD1; MED1; WNT4; PIAS1; ZNF107; EMX2; MYT1L; CUX1; SREBF1; CBFA2T3; NPM1; IL16; ELF3; CREB3L1; INSR; CERS4; KMT2A; TXNIP; TP63; FOXN3; BASP1; HOXB7; JUNB; ZHX2; TRIM22; MXI1; SATB1; HTATIP2; IFI16; MNDA; TGIF1; ZIC1; FOSB; TRIM29; KLF4
Down-regulation 42 HOXA5; BCOR; KLF1; TRPS1; ZNF134; ARID5A; KLF10; MED21; MED20; CD3D; TEAD3; PLAGL2; MED14; RNF4; AGO2; CRY1; NR4A3; MTDH; SMARCD3; ASH2L; WT1; C1QBP; RBPJ; TOX3; IRF7; RUNX3; AHR; MEOX1; EGR2; TRIM24; SMAD7; HMGB3; SNAI2; CITED2; ZBED2; CALR; ZBTB16; HOXB2; HES1; MAFB; ZNF512B; ID4