Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16277 Withaferin-a GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 316 KDM5A; CALCOCO1; HBP1; NCOA3; UBE2B; TSC22D3; ZNF473; ZNF419; EZH1; RBBP5; PHF1; TSG101; ATF3; TBP; JAK2; CIR1; ZBTB40; ZNF274; EGR1; DDIT3; MAFG; ZBTB48; ZNF304; SIRT7; TRIP11; SHOX; SAP130; VGLL4; ATF6; BACH1; ZNF212; PHIP; HINFP; MED23; HDAC5; BAZ2B; ZNF222; MXI1; ARID4A; HIVEP1; ZSCAN16; MEF2A; TMF1; ZNF14; ZNF8; ZFHX3; MED13; NR1H2; TFDP2; PEX14; NCOA2; NFYC; ZBTB43; MED6; ZNF12; DPF2; CBX4; ZNF79; ZNF211; BPTF; MZF1; BAZ2A; GABPB1; ATF4; NFE2L1; MXD4; TRAF6; ZMYM2; NFIL3; JUND; ZNF24; KDM2A; SUPT7L; ZNF764; BANP; CDK7; TFE3; CUX1; ZNF778; ZNF254; GON4L; RXRB; TBX3; TSC22D2; ZNF394; ATF7IP; TOX4; ARID4B; SIN3B; RLF; ZBTB25; PBXIP1; NFATC1; ZNF292; ZNF117; THAP3; ARID5B; ZBTB11; ING4; RNF111; BRD8; ARNT; ZKSCAN1; ETV2; SKIL; CSDC2; FOXO3; ZSCAN31; RING1; SOX21; PLAG1; PHF20; HCFC2; ZNF430; HTATIP2; HMBOX1; ZHX2; ZBTB17; MXD1; NFAT5; TRIM33; OVOL1; NCOA1; BRWD1; BTG1; STAT2; BRPF1; ERCC3; TCF7; BRF2; ZKSCAN5; SP2; NR5A1; ZNF557; MECP2; CREB3L1; AFF4; ID2; ZNF91; SP140L; SNIP1; TXNIP; NR3C2; ZNF408; GMEB2; IKZF3; RAX; RYBP; KMT2A; TULP3; TAF11; TAF7; NR1I3; NR4A1; ZNF235; SP100; LHX3; ELK4; AIP; NKX3-2; GCM1; ZNF23; REL; IRF9; ATOH1; ARID5A; ZNF136; SNW1; LYL1; NKX3-1; IRF7; PAWR; FOXJ3; SKI; PRDM2; PAX8; MAFF; ZNF652; ZNF331; NPAS1; BLZF1; ZNF189; JUNB; RSF1; TULP1; ZNF44; CBX7; ZNF34; PRDM10; PAX9; YAF2; NR1D2; ARID3A; BTAF1; MDM4; GATA1; GABPA; ZNF184; SUMO1; PITX3; WNT4; YAP1; GATA3; BBX; ZNF10; ZNF432; TBL1XR1; SSX1; DBP; ZNF345; BARX1; TLX3; MSX1; ZNF140; TRIB3; ZNF468; ZNF175; NPAT; KLF13; ZNF444; SUPT4H1; CHD1; ZBTB7A; HOXD3; RUNX3; ZNF350; SIM2; MED17; ZNF721; HOXB2; HOXB13; ING1; KLF3; ZNF426; MYCL; SERTAD2; TTF1; CAMTA1; LPIN2; USP16; FOSL2; WWP1; KLF4; SRY; NFE2; ERBB4; SOX3; CREB3L2; DDX17; PSPC1; GTF2F1; FOS; TAL1; ZNF83; GATA6; PEX2; EGR3; KAT2B; SIX1; AGO2; SPEN; FOSB; ZNF467; ING3; BCL6; SHOX2; CBFA2T3; CREB5; DLX5; CERS4; XBP1; SIX2; ZNF423; ZNF264; VGLL1; CHD9; PIR; ECD; HIPK1; HOXD1; MED1; INSR; ZIC1; NR4A2; ZNF266; BCL11A; DLX2; ZNF232; CD3D; RREB1; OSR2; NKX2-1; MEOX2; ZEB1; FOXN3; FOXF1; TCF4; FOXD1; HOXB6; ELF5; SMAD6; MECOM; FOXC1; TRIM29; JARID2; FOXO4; MAF; MITF; TLE4; TFAP2C; CREB1; MAFB; MAGED1; RELB; VPS72; BHLHE41
Down-regulation 110 CCNA2; TFDP1; MYC; RUVBL1; DNMT1; C1QBP; HMGA2; CDK2; FOXM1; CEBPD; HDAC2; SMARCC1; PA2G4; SSRP1; CBX5; TCERG1; SF1; NRIP1; WWTR1; PARP1; MYBL2; HDAC6; ADRB2; PMS1; NELFB; MYCBP; NOC2L; RHOA; WHSC1; RNF138; GTF2I; WDR77; SOX4; RAN; TRIM28; RUVBL2; HMGB3; THAP4; NPM1; PRKDC; HMGA1; SUB1; TP53; HES1; ATF1; HMGB1; UBE2I; RBBP4; RBL1; HOXA5; GTF3A; ZNF532; PTTG1; ALX1; PPRC1; DR1; BAZ1B; RBBP8; BAZ1A; LIN28A; HNRNPD; HOXC4; ILF2; SRF; UBP1; HMGB2; HOXA10; SLC2A4RG; LZTS1; CBX3; POU5F1B; APEX1; DEK; TFCP2; CAPN15; CHD7; SMARCD2; NAB1; NFIB; MED24; CARM1; SNAI2; CBFB; TEAD4; ZBED4; MYBL1; CENPF; ZNF239; NR2F1; LOXL2; SUV39H1; YWHAB; ZNF22; RBM14; MTA1; BMI1; NKX2-2; TGFB1I1; CEBPZ; ESR1; NANOG; BCLAF1; ID1; STAT3; HMGN3; MEIS1; TCFL5; ZFP36L1; IKBKAP; PBX1