Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16276	Withaferin-a	GSE70138	MCF10A	Human	24h	10uM	EID0005

Response Information :

Types	Number	Response transcription factors
Up-regulation	66	EGR1; JUNB; ATF3; BTG1; FHL2; ATF4; MYBL2; ZNF532; CALCOCO1; ZNF222; CBX4; RELA; FOSB; PPARD; IRF7; FOS; TSC22D3; NR4A1; CDX1; GATA2; SNAI2; DNAJC1; PNRC1; GABPB1; SUPT4H1; HBP1; ZNF140; ZBED2; SPIB; SP110; SOX9; MEF2C; HDAC9; CCNE1; BASP1; XBP1; HOXD3; HOXB13; CREB3L1; DLX5; KLF4; TULP3; MEOX1; LITAF; TP63; ZNF302; DLX2; IRF9; TCF4; SOX2; IRF6; LMCD1; HOXD1; IRF8; JUP; MITF; TRIM29; HIC2; MYCN; ZSCAN18; ZNF423; SOX17; MEIS2; TFAP2C; ID1; FOXO4
Down-regulation	75	MYC; CCNA2; ADRB2; NFKBIA; PRKDC; HDAC2; CENPF; HOXA5; NR3C1; MKL2; CRK; NRIP1; RB1; KAT6A; PMS1; NFIB; TCF12; SP3; CCNC; BIRC2; GTF2I; PAXBP1; SMARCA5; AHR; WWTR1; CHD4; RBBP4; BAZ1A; MTDH; HMGB2; KMT2A; NFIL3; C1D; RNF138; SUZ12; SAP30; HES1; MDM2; ZNF721; PHF20; FUBP1; SPEN; HMGXB4; SMARCD2; EHMT2; CHD9; COPS2; BMI1; CEBPA; BRCA1; HDAC4; CEBPZ; NCOA6; HIPK3; TRRAP; TBL1XR1; RBBP8; ZNF217; HOXC6; SMAD1; SUB1; AFF1; ELK3; BCLAF1; FOXJ3; ZBTB18; HOXB7; BHLHE40; HOXC10; HOXB6; SCAND1; HOXB2; PURA; MYBL1; MYRF