Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16274 Mitoxantrone GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 49 ZNF274; RFX5; TRIM22; CALCOCO1; ID2; NEDD8; TSG101; KAT6B; TBX3; NAB1; MDM2; HBP1; TSC22D3; TAF7; BASP1; AES; STAT6; SP110; IRF9; KLF5; PPARGC1A; TOX3; SIAH2; TFEC; ZNF302; SMAD3; ZNF32; DDX5; ZBED2; STAT1; TRIM29; ETS2; SMAD7; ZEB2; SMARCA1; ELF3; FOXC1; TSC22D1; BCL3; ATF3; HMGN3; ZIC1; TOX; TGIF1; TXNIP; MAF; FOS; ELK3; SOX9
Down-regulation 45 CCNA2; HOXA5; FOXM1; CENPF; TAF5; EZH2; WHSC1; KMT5A; C1QBP; TAF1A; MYBL2; TCF21; ILF2; RAD21; TBL1X; CARM1; PITX2; PCGF1; PAWR; HOXB2; MTDH; NCOA6; ETV5; AEBP1; AGO2; HMGB2; HOXD11; ZEB1; PTTG1; HOXB7; TOB1; TBL1XR1; ZFP36L2; BATF3; TGFB1; FLNA; BACH2; WT1; ID4; CREB1; MYBL1; SCAND1; SATB2; MEIS2; SUV39H1